100000 - Document - Document and Entity Information
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100010 - Statement - CONSOLIDATED BALANCE SHEETS
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100020 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)
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100030 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS
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100040 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)
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100050 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS
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100060 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical)
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100070 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995455 - Disclosure - Organization and Operations
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995485 - Disclosure - Investments
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995495 - Disclosure - Loss per Share
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995505 - Disclosure - Composition of Certain Financial Statement Captions
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995515 - Disclosure - Commitments and Contingencies
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995525 - Disclosure - License Agreements
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995535 - Disclosure - Term Loan Obligations
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995545 - Disclosure - Line of Credit Facility
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995555 - Disclosure - Grant Revenue
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995565 - Disclosure - Biocept Asset Acquisitions
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995575 - Disclosure - Income Taxes
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995585 - Disclosure - Employee Benefit Plan
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995595 - Disclosure - Stockholders' Equity
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995605 - Disclosure - Share-based Compensation
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995615 - Disclosure - Segment Information
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995625 - Disclosure - Subsequent Events
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995635 - Disclosure - Financial Statement Schedules
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995645 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995655 - Disclosure - Fair Value Measurements (Tables)
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995665 - Disclosure - Loss per Share (Tables)
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995675 - Disclosure - Composition of Certain Financial Statement Captions (Tables)
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995685 - Disclosure - Commitments and Contingencies (Tables)
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995695 - Disclosure - Term Loan Obligations (Tables)
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995705 - Disclosure - Income Taxes (Tables)
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995715 - Disclosure - Share-based Compensation (Tables)
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995725 - Disclosure - Segment Information (Tables)
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995735 - Disclosure - Organization and Operations - Additional Information (Details)
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995745 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995755 - Disclosure - Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details)
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995765 - Disclosure - Fair Value Measurements - Summary of Key Inputs Used in Valuation of Liability Classified Warrants (Details)
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995775 - Disclosure - Fair Value Measurements - Schedule of Change in Fair Value of Warrant Liabilities (Details)
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995785 - Disclosure - Fair Value Measurements - Additional Information (Details)
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995795 - Disclosure - Investments - Additional Information (Details)
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995805 - Disclosure - Loss per Share - Schedule of Computation of Basic and Diluted Net Loss Per Share of Common Stock (Details)
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995815 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Annual Lease Payments under Operating Leases (Details) 2
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995825 - Disclosure - Loss per Share - Schedule of Antidilutive Securities Excluded from Diluted (Loss) per Share (Details)
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995835 - Disclosure - Composition of Certain Financial Statement Captions - Other Current Assets (Details)
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995845 - Disclosure - Composition of Certain Financial Statement Captions - Property and Equipment, Net (Details)
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995855 - Disclosure - Composition of Certain Financial Statement Captions - Additional Information (Details)
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995865 - Disclosure - Composition of Certain Financial Statement Captions - Intangible Assets, Net (Details)
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995875 - Disclosure - Composition of Certain Financial Statement Captions - Future Amortization Expense on Intangible Assets (Details)
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995885 - Disclosure - Composition of Certain Financial Statement Captions - Accounts Payable and Accrued Expenses (Details)
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995895 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995905 - Disclosure - Commitments and Contingencies - Summary of Lease Costs (Details)
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995915 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Annual Lease Payments under Operating Leases (Details)
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995925 - Disclosure - License Agreements - Additional Information (Details)
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995935 - Disclosure - Term Loan Obligations - Additional Information (Details)
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995945 - Disclosure - Line of Credit Facility - Additional Information (Details)
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995955 - Disclosure - Grant Revenue - Additional Information (Details)
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995965 - Disclosure - Biocept Asset Acquisitions - Additional Information (Details)
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995975 - Disclosure - Income Taxes - Additional Information (Details)
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995985 - Disclosure - Income Taxes - Reconciliation of Total Income Tax Provision (Details)
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995995 - Disclosure - Income Taxes - Deferred Tax Assets and Liabilities (Details)
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996005 - Disclosure - Income Taxes - Unrecognized Tax Benefits Activity (Details)
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996015 - Disclosure - Employee Benefit Plan - Additional Information (Details)
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996025 - Disclosure - Stockholders' Equity - Preferred Stock (Details)
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996035 - Disclosure - Stockholders' Equity - Common stock (Details)
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996045 - Disclosure - Share-based Compensation - Additional Information (Details)
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996055 - Disclosure - Share-based Compensation - Stock Option Activity (Details)
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996065 - Disclosure - Share-based Compensation - Weighted-average Assumptions (Details)
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996075 - Disclosure - Share-based Compensation - Summary of Share-Based Compensation Recognized (Details)
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996085 - Disclosure - Segment Information - Additional Information (Details)
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996095 - Disclosure - Segment Information - Schedule of Segment Expenses (Details)
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996105 - Disclosure - Subsequent Events - Additional Information (Details)
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Statement [Line Items]
Statement [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Weighted Average Remaining Contractual Life (years) [Roll Forward]
Debt Instrument [Axis]
Debt Instrument
May 2024 Private Placement [Member]
May 2024 private placement.
Cybersecurity Risk Board of Directors Oversight [Text Block]
Income tax contingency.
Income Tax Contingency [Abstract]
Income Tax Contingency [Abstract]
Plan Name [Domain]
Plan Name
Purchase of treasury stock
Purchase of treasury stock
Payments for Repurchase of Equity
Payments for Repurchase of Equity, Total
Facility And Other Overhead Expenses [Member]
Facility And Other Overhead Expenses [Member]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
New Capital Subscriptions [Member]
New Capital Subscriptions.
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Business Combination, Acquisition Related Costs
Costs of acquisitions
ASU - 2024-03
Accounting Standards Update 2024 03 [Member]
Accounting standards update 2024 03.
Interest Paid, Excluding Capitalized Interest, Operating Activities
Interest
Number of Operating Segments
Number of operating segment
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2028
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable at December 31, 2024 (in dollars per share)
Income Tax Authority, Name [Domain]
Shares, Outstanding
Balance (in shares)
Balance (in shares)
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Auditor Name
Auditor Name
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Cash Deposits
Cash deposits.
Cash deposits
Long-Term Debt, Current Maturities
Term loan obligation, current
Long-Term Debt, Current Maturities, Total
Term loan obligation, current
Investments
Investments, Total
Total investments
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Two thousand twenty two distribution agreement.
Two Thousand Twenty Two Distribution Agreement [Member]
2022 Distribution Agreement [Member]
Schedule of right of use assets and lease liabilities.
Schedule Of Right Of Use Assets And Lease Liabilities Table [Text Block]
Summary of Lease Liabilities and Right-of-Use Assets
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of Change in Fair Value of Warrant Liabilities
Product and Service [Axis]
Product and Service
Finite-Lived Intangible Assets by Major Class [Axis]
Depreciation, Depletion and Amortization
Depreciation and amortization
Depreciation, Depletion and Amortization, Total
Lorem Vascular, Pte. Ltd.
Lorem Vascular Pte Ltd [Member]
Lorem Vascular Pte Ltd [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Stock option vesting percentage
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Stock Repurchased During Period, Shares
Number of stock repurchased
Payments to Acquire Productive Assets
Payments to Acquire Productive Assets, Total
Total cash payment
Cybersecurity Risk Management Processes Integrated [Text Block]
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense
Equity [Text Block]
Stockholders' Equity
Class of Warrant or Right [Axis]
Class of Warrant or Right
Revenue from Contract with Customer [Text Block]
Grant Revenue
Cash Paid During Period For [Abstract]
Cash paid during period for:
Cash paid during period for:
Debt Securities, Available-for-Sale, Unrealized Loss
Unrealized loss on available-for-sale
Total unrealized loss on available-for-sale securities
Congressionally Directed Medical Research Programs [Member]
Congressionally Directed Medical Research Programs [Member]
Congressionally directed medical research programs.
Sale of Stock [Domain]
Sale of Stock
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents [Domain]
Change In Fair Value Of Warrants
Change in fair value of warrants.
Change in fair value of warrants
Change in fair value of warrants
Two thousand eighteen rights offering.
Two Thousand Eighteen Rights Offering [Member]
2018 Rights Offering [Member]
Two thousand and twenty two purchase agreement.
Two Thousand and Twenty Two Purchase Agreement [Member]
2022 Purchase Agreement [Member]
Warrant, Exercise Price, Decrease
Reduction of exercise price of Warrants
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Entity Central Index Key
Entity Central Index Key
Debt Securities, Available-for-Sale [Line Items]
Preferred stock dividend rate percentage eliminated date.
Preferred Stock Dividend Rate Percentage Eliminated Date
Series A 3.6% Convertible preferred stock eliminated date
Warrant [Member]
Outstanding Warrants [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Cancelled/forfeited (in shares)
Auditor Opinion [Text Block]
Auditor Opinion
Increase (Decrease) in Operating Capital [Abstract]
Increases (decreases) in cash caused by changes in operating assets and liabilities:
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Initial Subscription [Member]
Initial Subscription.
Common Stock, Shares, Issued
Common stock, shares issued (in shares)
Rights related to distribution of assets
Rights Related To Distribution Of Assets
Rights related to distribution of assets.
SPEA Warrants [Member]
SPEA Warrants.
Percentage of grant proceeds with interest not exceed annually.
Percentage Of Grant Proceeds With Interest Not Exceed Annually
Percentage of grant proceeds with interest not exceed annually
Stock Issued During Period, Value, Reclassification of warrants to equity
Stock issued during period, value, reclassification of warrants to equity.
Reclass of warrants to equity
Fair Value Measurement Inputs and Valuation Techniques [Table]
Short-Term Debt [Text Block]
Line of Credit Facility
Preferred Stock [Member]
Convertible Preferred Stock [Member]
Income Statement [Abstract]
Entity Address, State or Province
Entity Address, State or Province
Payments to Acquire Short-Term Investments
Purchases of short-term investments
Collateralized marketable securities
Marketable Securities
Marketable Securities, Total
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Interest related to unrecognized tax benefits in interest expense and penalties
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
2027
Finite-Lived Intangible Asset, Expected Amortization, Year Three
Common stock, sales, available for issuance.
Common Stock Sales Available For Issuance
Remaining availability under financing facility
Deferred tax assets valuation allowances.
Deferred Tax Assets Valuation Allowances
Valuation allowance
Warrants
Warrants Policy [Policy Text Block]
Warrants Policy.
Lease, Cost [Abstract]
Lease expense:
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Exercisable at December 31, 2023
Liability Class [Axis]
Exercise of pre-funded warrants (in Shares)
Exercise Of Pre-funded Warrants Shares
Exercise of pre-funded warrants shares.
Series F Preferred Stock [Member]
Treasury stock, shares
Treasury Stock, Common, Shares
Cover
Cover [Abstract]
License agreement abstract.
License Agreement [Abstract]
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Net loss per share of common stock - basic
Second amendment to the amended and restated loan and security agreement.
Term Loan [Member]
Term Loan [Member]
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase (decrease) in valuation allowance
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend
Operating Expenses [Abstract]
Operating expenses:
Series A convertible preferred stock.
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock [Member]
Fair Value, Measurement With Unobservable Inputs Reconciliation, Recurring Basis, Liability, Reclassification To Equity
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liability, reclassification to equity.
Reclassification to equity
Document Annual Report
Document Annual Report
Asset Acquisition [Axis]
Investments, Debt and Equity Securities [Abstract]
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Plan Name [Axis]
Plan Name
Segment Reporting [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Balance as of December 31, 2023 (in shares)
Balance as of December 31, 2024 (in shares)
Assets, Current [Abstract]
Current assets:
Common stock capital shares reserved for future issuance
Increased in the total number of shares of common stock reserved for issuance
Number of shares reserved for issuance and sale
Investment Type [Axis]
Investment Type
Deferred Tax Liabilities, Net
Net deferred tax assets (liability)
September two thousand and twenty two distribution agreement.
September Two Thousand and Twenty Two Distribution Agreement [Member]
September 2022 Distribution Agreement [Member]
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Net cash used in operating activities
Common stock issued in payment for in process research and development
Stock Issued
Product and Service [Domain]
Product and Service
Lessee, Operating Lease, Term of Contract
Lessee, operating lease, term of contract
Maximum value of shares to be issued under agreement.
Maximum Value of Shares to be Issued Under Agreement
Maximum value of shares to be issued under agreement
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Operating Loss Carryforwards
Tax loss carryforwards
Recorded Unconditional Purchase Obligation by Category of Item Purchased [Axis]
Recorded Unconditional Purchase Obligation by Category of Item Purchased
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Cash flows used in operating activities:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Recurring Basis [Member]
Fair Value, Recurring [Member]
Other Income and Expenses [Abstract]
Other income (expense):
Common Stock, Par or Stated Value Per Share
Common stock, par value (in dollars per share)
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Measurement Input Type [Domain]
Statement of Cash Flows [Abstract]
February Two Thousand Twenty Five Securities Purchase and Exchange Agreements [Member]
February two thousand twenty five securities purchase and exchange agreements.
February 2025 SPEA Agreements
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development studies.
Accrued Research And Development Studies
Accrued R&D studies
Stock based compensation 2015 equity incentive plan 1 member.
Stock Based Compensation2015 Equity Incentive Plan1 [Member]
2015 Plan [Member]
Available-For-Sales and Short-Term Investments Date of Purchase Term
Available-for-sales and short-term investments date of purchase term.
Available-for-sales and short-term investments date of purchase term
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease)
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease), Total
Change in fair value of warrants
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Number of shares callable by warrants (in shares)
Number of securities called by warrant or right
Entity [Domain]
Entity
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Redemption of Short-Term Investments
Redemption of Short-Term Investments
Redemption of short-term investments
Canaccord Genuity L L C Member
Canaccord Genuity L L C [Member]
Canaccord Genuity LLC [Member]
Canaccord Genuity LLC [Member]
Deferred Tax Assets, Other
Other, net
Pershing Credit Facility [Member]
Pershing Credit Facility [Member]
Pershing Credit Facility.
Equity Components [Axis]
Equity Components
Recorded Unconditional Purchase Obligation [Line Items]
Recorded Unconditional Purchase Obligation [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Charlottesville
Charlottesville [Member]
Charlottesville [Member]
Class of Warrant or Right Expiration Period
Class of warrant or right expiration period.
Expiration period
Schedule of Computation of Basic and Diluted Net Loss Per Share of Common Stock
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Accrued vacation and compensation, current.
Accrued Vacation And Compensation Current
Accrued vacation and compensation
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Intangible Asset, Finite-Lived [Table]
Effective income tax rate reconciliation tax return to provision.
Effective Income Tax Rate Reconciliation Tax Return To Provision
Return to provision
Return to provision
Subsequent Event Type [Axis]
Subsequent Event Type
Nonoperating Income (Expense)
Total other income
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Diluted (Loss) per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
The expiration date of each operating loss carryforward included in total operating loss carryforwards, or the applicable range of such expiration dates.
Operating Loss Carryforwards Expiration Dates1
Net operating loss carryforwards, Expire date
Investments
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Research credit
Research credit
Entity Voluntary Filers
Entity Voluntary Filers
Disclosure of accounting policy for license agreement.
License Agreement Disclosure [Text Block]
License Agreements
Finite-Lived Intangible Asset, Expected Amortization, Year Two
2026
Amendment Flag
Amendment Flag
Increase (Decrease) in Operating Lease Liability
Change in operating lease liabilities
Operating Lease, Liability, Noncurrent
Noncurrent operating lease liability
Operating lease liabilities. noncurrent
Prefunded Warrant [Member]
Prefunded Warrant.
Common stock issued for research and development
Common Stock Issued for Research and Development
Common stock issued for research and development.
Options.
Options [Member]
Outstanding Stock Options [Member]
Domestic Tax Jurisdiction [Member]
Federal [Member]
Debt Instrument, Name [Domain]
Debt Instrument, Name
Preferred stock, voting rights
Preferred Stock, Voting Rights
Net loss
Net loss
Aggregate Purchase Price
Aggregate purchase price.
Aggregate purchase price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Exercisable at December 31, 2024
Variable Rate [Domain]
Variable Rate
Research and Development Expense [Member]
Research and Development [Member]
Other.
Other
Other
Schedule of Debt [Table Text Block]
Face Value to Book Value Reconciliation
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Loss on disposal of property and equipment
Equity Component [Domain]
Equity Component
Professional Expenses [Member]
Professional expenses.
Statistical Measurement [Domain]
Statistical Measurement
Document Financial Statement Error Correction [Flag]
General and Administrative Expense
General and administrative
Total general and administrative
Segment Reporting, Expense Information Used by CODM, Type [Extensible Enumeration]
Deferred Income, Noncurrent
Deferred grant liability
Financing Expense
Financing expense.
Financing expense
Financing expense
Supplemental Balance Sheet Disclosures [Text Block]
Composition of Certain Financial Statement Captions
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Stock option contractual term
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Components of Deferred Tax Liabilities [Abstract]
Deferred tax liabilities [Abstract]
Treasury Stock [Member]
Treasury Stock, Common [Member]
Cybersecurity Risk Management Processes Integrated [Flag]
Proceeds from Lines of Credit
Proceeds from Lines of Credit, Total
Proceeds from credit facility
Schedule of Other Current Assets [Table Text Block]
Other Current Assets
Preferred Stock, Shares Issued
Preferred stock, shares issued (in shares)
Operating Lease, Payments
Operating cash used for operating leases
US Government Corporations and Agencies Securities [Member]
Government Agency Bonds [Member]
Lincoln park capital fund, LLC.
Lincoln Park Capital Fund L L C [Member]
Lincoln Park Capital Fund, LLC [Member]
Operating lease discount rate
Lessee, Operating Lease, Discount Rate
Consideration paid to preferred stock holders
Consideration Paid To Preferred Stock Holders
Consideration paid to preferred stock holders.
Deferred Tax Liabilities, Other
Other
Short-Term Investments
Short-Term Investments, Total
Investments
Operating Lease, Expense
Rent expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Vested and expected to vest at December 31, 2024 (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled/forfeited (in dollars per share)
Increase Decrease In Grant Receivable
Increase decrease in grant receivable.
Grant receivable
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Class of Stock [Domain]
Class of Stock
Refers to the period exercisable from the date of issuance.
Period Exercisable From The Date Of Issuance
Period exercisable from the date of issuance
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Intangible Assets, Net
Common Stock, Shares, Outstanding
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Finite-Lived Intangible Assets, Major Class Name [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Options [Roll Forward]
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value (in dollars per share)
Deferred Tax Asset, In-Process Research and Development
Capitalized R&D
Contract effective date.
Contract Effective Date
Contract effective date
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Proceeds from Issuance or Sale of Equity
Proceeds from Issuance or Sale of Equity, Total
Proceeds from sale of common stock warrants and pre-funded warrants, net
May 2024 Purchase Agreement
May Two Thousand Twenty Four Purchase Agreement [Member]
May two thousand twenty four purchase agreement.
Asset Acquisition [Abstract]
Finite-Lived Intangible Assets [Line Items]
Intellectual Property [Member]
Intellectual Property [Member]
Entity Interactive Data Current
Entity Interactive Data Current
Warrant liability.
Warrant Liability [Member]
Warrant Liability [Member]
Debt Instrument, Redemption Price, Percentage
Principal amount, Percentage
Accounting Standards Update [Domain]
Accounting Standards Update
Maximum beneficial ownership percentage
Maximum Beneficial Ownership Percentage
Maximum beneficial ownership percentage.
Statistical Measurement [Axis]
Statistical Measurement
Operating Lease, Cost
Operating lease expense
Income taxes.
Income Taxes [Table]
Income Taxes [Table]
Fair Value
Assets, Fair Value Disclosure
Assets, Fair Value Disclosure, Total
Related and Nonrelated Parties [Domain]
Related Party
Lease, Cost
Total lease expense
Summary of Future Minimum Annual Lease Payments under Operating Leases
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Finite-Lived Intangible Assets, Gross
Finite-Lived Intangible Assets, Gross, Total
Gross Carrying Amount
Initial commitment shares.
Initial Commitment Shares
Initial commitment shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Securities remaining and available for future issuances (in shares)
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Weighted average period for recognition of cost
Proceeds from Issuance of Private Placement
Proceeds from private placement
Research and Development Expense, Policy [Policy Text Block]
Research and Development
Statement of Income Location, Balance [Axis]
Income Statement Location
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents [Axis]
Assets
Total assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term
Amount of lessee's undiscounted obligation for lease payments for operating lease, due after fourth fiscal year following latest fiscal year.
Lessee Operating Lease Liability Payments Due After Year Four
Thereafter
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Commitment fee.
Commitment Fee [Member]
Commitment Fee [Member]
Deferred Tax Liabilities, Gross
Total deferred tax liability
Deferred Tax Liabilities, Gross, Total
Offering Costs
Offering costs.
Offering cost
Offering expenses
Recorded Unconditional Purchase Obligation, Category [Domain]
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Issued Accounting Pronouncements
Entity Address, City or Town
Entity Address, City or Town
March Two Thousand Twenty Five Private Placement [Member]
March Two Thousand Twenty Five Private Placement.
March 2025 Private Placement
Auditor Location
Auditor Location
Payment of offering costs related to sale of common stock
Payment of offering costs related to sale of common stock
Payments of Stock Issuance Costs
Issuance costs paid in common stock
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Reconciliation of the total income tax provision tax rate [Abstract]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Sale of Stock, Percentage of Ownership after Transaction
Securities being sold in offering
Contract termination date.
Contract Termination Date
Contract termination date
Schedule of operating and financing lease liability maturity.
Schedule Of Operating And Financing Lease Liability Maturity Table [Text Block]
Summary of Future Minimum Annual Lease Payments under Operating and Financing Leases
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Summary of Share-Based Compensation Recognized
Debt Instrument, Face Amount
Original loan amount
Aggregate principal amount
Effective Income Tax Rate Reconciliation Financing Expense
Effective income tax rate reconciliation financing expense.
Financing expense
Depreciation
Depreciation expense
Depreciation, Total
Share Price
Offering price
Schedule of Segment Reporting Information, by Segment [Table]
Sale closed date
Sale of Stock, Transaction Date
Software [Member]
Computer Software, Intangible Asset [Member]
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Private Placement Share [Member]
Private Placement [Member]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Share based compensation
Share-based compensation
Share-Based Payment Arrangement [Text Block]
Share-based Compensation
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Prepaid Expense and Other Assets, Current [Abstract]
Other Current Assets [Abstract]
Cash paid for amounts included in the measurement of lease liabilities.
Cash Paid For Amounts Included In Measurement Of Lease Liabilities
Total cash paid for amounts included in the measurement of lease liabilities
Percentage of net operating loss carryforwards available for offsetting against future taxable income.
Percentage Of Net Operating Loss Carryforwards Available For Offsetting Against Future Taxable Income
Percentage of federal net operating losses used to offset of future taxable income
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, weighted average discount rate
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Grant [Member]
Grant [Member]
Fair Value Disclosures [Abstract]
Grant funding term.
Grant Funding Term
Grant funding term
Entity Public Float
Entity Public Float
Issue and sale of stock, net
Stockholders' equity requirement
Sale and issuance of common stock, net
Deferred Tax Assets, Net of Valuation Allowance
Total deferred tax assets, net of allowance
Stock Issued During Period, Value, Stock Options Exercised
Stock options exercised
Liabilities, Current [Abstract]
Current liabilities:
Redemption of Series F preferred stock (in shares)
Stock Redeemed or Called During Period, Shares
Document Type
Document Type
Accounting Standards Update [Axis]
Accounting Standards Update
Asset Impairment Charges
Impairment charges
Asset Impairment Charges, Total
Impairment related to long lived assets or goodwill
Title of 12(b) Security
Title of 12(b) Security
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Lease, Cost [Table Text Block]
Summary of Lease Costs
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Statement of Stockholders' Equity [Abstract]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Beginning balance
Ending balance
Document Fiscal Period Focus
Document Fiscal Period Focus
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Exercisable at December 31, 2024
Research and development
Research and development expense
Research and Development Expense
Total research and development
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted (in shares)
Common stock shares to be issued (in shares)
Indefinite-Lived Intangible Assets [Axis]
Preferred Stock, Dividend Rate, Percentage
Convertible preferred stock
Property, Plant and Equipment, Gross
Property and equipment, gross
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Subsequent Event Type [Domain]
Subsequent Event Type
Maximum Beneficial Ownership Percentage By Election Of Holder
Maximum beneficial ownership percentage by election of holder.
Maximum beneficial ownership percentage by election of holder
Share-Based Payment Arrangement, Activity [Table Text Block]
Stock Option Activity
Expected Term [Member]
Measurement Input, Expected Term [Member]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Weighted-average Assumptions
Initial commitment fee.
Initial Commitment Fee
Initial commitment fee paid in cash
Initial commitment fee
Aggregate expense including fee and disbursement expenses.
Aggregate Expense Including Fee and Disbursement Expenses
Reimburse of fee and disbursements expenses
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrant exercise price (in dollars per share)
Financial Instruments [Domain]
Financial Instruments
Series F Convertible Preferred Stock [Member]
Series F Convertible Preferred Stock.
Warrants Remain Outstanding, Percentage
Warrants remain outstanding, percentage
Warrants remain outstanding, percentage
Sale of Stock [Axis]
Sale of Stock
Cash flows used in investing activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Investments [Domain]
Investments
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue recognized
Grant revenue
Income Tax Disclosure [Text Block]
Income Taxes
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Gross decreases – tax positions in prior period
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Reconciliation of Total Income Tax Provision
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Deferred Income, Current
Deferred grant liability
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Clinical Development and Licensing Expenses [Member]
Clinical Development and Licensing Expenses.
Clinical, Development and Licensing Expenses [Member]
Line of Credit Facility [Line Items]
Credit Facility [Domain]
Aggregated Intrinsic Value [Roll Forward]
Share Based Compensation Arrangement by Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Share based compensation arrangement by share based payment award options aggregate intrinsic value.
Accounting Standards Update 2023-07 [Member]
ASU - 2023-07
Finite-Lived Intangible Assets, Net
Beginning Balance
Ending Balance
Intangible Asset, Net
Debt Securities, Available-for-Sale [Table]
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Refers to cumulative change in ownership in percentage.
Cumulative Change In Ownership
Cumulative change in ownership
Entity Address, Address Line Two
Entity Address, Address Line Two
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Black-Scholes-Merton option valuation model based on weighted-average assumptions [Abstract]
Litigation Case [Domain]
Litigation Case
Liabilities and Stockholders' Equity (Deficit)
Liabilities and Equity [Abstract]
Document Period End Date
Document Period End Date
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Nano Tx license agreement Member
Nano Tx Licenses Agreement [Member]
Nano Tx Licenses Agreement [Member]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Effective Income Tax Rate Reconciliation, Percent
Total income tax provision
Stockholders' Equity Note [Abstract]
Percentage issuance of common stock.
Percentage Issuance Of Common Stock
Percentage issuance of common stock
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
State tax credit carryforwards
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Dilutive common shares excluded from the calculations of diluted loss per share (in shares)
Operating leases, expiry year.
Operating Leases Expiry Year
Operating leases expiry year
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Share-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Consideration to purchaser in cash
Sale of Stock, Consideration Received on Transaction
Deferred CPRIT grant revenue
Deferred Revenue
Deferred Revenue, Total
Refers to the period of net operating loss and R&D tax credit carry forwards to offset future taxable income.
Net Operating Loss And Research And Development Tax Credit Carry Forwards To Offset Future Taxable Income Period
Period of net operating loss and R&D tax credit carry forwards to offset future taxable income
Research and development award in period
Research And Development Award In Period
Research and development award in period.
Income Tax Expense (Benefit)
Provision or benefit for income taxes
Income Tax Expense (Benefit), Total
Percentage of non-dilutive monetary awards required to pay.
Percentage of Non-dilutive Monetary awards Required to Pay
Percentage of non-dilutive monetary awards required to pay
Income Tax Authority, Name [Axis]
Components of Deferred Tax Assets [Abstract]
Deferred tax assets [Abstract]
Series C convertible preferred stock.
Series C Convertible Preferred Stock [Member]
Series C Convertible Preferred Stock [Member]
Trading Symbol
Trading Symbol
First payment received
First Payment Received
First Payment Received
Variable Rate [Axis]
Variable Rate
Total stockholders' equity (deficit)
Stockholders' deficit
Equity, Attributable to Parent
Balance
Balance
SEC Schedule, 12-09, Valuation and Qualifying Accounts [Abstract]
Contractual obligation to provide funding of research and development costs over periods that initially exceed one year or the normal operating cycle, if longer.
Pre Clinical Research Study Obligations [Member]
Pre-clinical Research Study Obligations [Member]
Refers to period for material changes of liability for uncertain tax benefits.
Period For Material Changes Of Liability For Uncertain Tax Benefits
Period for material changes of liability for uncertain tax benefits
Deferred Tax Assets, Gross
Total deferred tax assets
Share-Based Payment Arrangement [Policy Text Block]
Share-Based Compensation
Debt Instrument, Convertible, Conversion Price
Conversion price
Sale of Stock, Number of Shares Issued in Transaction
Number of shares issued
In Process Research and Development, Policy [Policy Text Block]
Acquired In-Process Research and Development (IPR&D)
Cybersecurity Risk Management, Strategy, and Governance [Table]
Goodwill
Goodwill
Goodwill, Total
Goodwill, Beginning Balance
Goodwill, Ending Balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Issuances
Issuance of warrants
Change in accounting principle, accounting standards update, adopted
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Total unamortized compensation cost related to outstanding unvested stock options and restricted stock awards
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Liability for Uncertainty in Income Taxes, Current
Liability for uncertain tax positions
Additional Subscription [Member]
Additional Subscription.
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Defined Contribution Plan, Employer Discretionary Contribution Amount
Discretionary or matching contributions
Series B convertible preferred stock.
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Measurement Input Type [Axis]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
January two thousand and twenty two distribution agreement.
January Two Thousand and Twenty Two Distribution Agreement [Member]
January 2022 Distribution Agreement [Member]
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and cash equivalents
Percentage of aggregate amount of proceeds awarded under CPRIT grant.
Percentage Of Aggregate Amount Of Proceeds Awarded Under CPRIT Grant
Percentage of aggregate amount of proceeds awarded under CPRIT grant
Number Of Votes Per Share
Number Of Votes Per Share
Number of votes per share.
Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]
Fair Value Measurements
Class of Stock [Line Items]
Class of Stock [Line Items]
Measurement Input, Price Volatility [Member]
Expected Volatility [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividends
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Security Exchange Name
Security Exchange Name
Fair Value by Liability Class [Domain]
Deferred Tax Assets, Tax Credit Carryforwards
Income tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Total
Maintain Minimum Market Value of Listed Securities
Maintain minimum market value of listed securities
Maintain minimum market value of listed securities
Operating Expenses
Total operating expenses
Measurement Input, Risk Free Interest Rate [Member]
Risk-free Interest Rate [Member]
Issuance of common stock for in process research and development
Stock Issued During Period, Value, Issued for Services
Class of Stock [Axis]
Class of Stock
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Legal Entity [Axis]
Legal Entity
Tax credit carryforward, expiration date
Expiration date of the tax credit carryforward.
Tax Credit Carryforward Expiration Date1
CPRIT grant funding term.
CPRIT Grant Funding Term
CPRIT grant funding term, description
Lessee, Operating Lease, Liability, to be Paid, Year Three
2027
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Resulting fair value
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Subsequent Event [Member]
Subsequent Event [Member]
Maximum [Member]
Maximum [Member]
Total liabilities and stockholders' equity (deficit)
Liabilities and Equity
Operating lease right-use-of assets
Operating lease right-of-use assets
Operating
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flows information:
Prime Rate [Member]
Prime Rate [Member]
Retirement Benefits [Abstract]
Property, Plant and Equipment, Impairment [Policy Text Block]
Impairment
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share, diluted
Net loss per share of common stock - diluted
Asset Acquisition [Line Items]
Liabilities
Total liabilities
Unrecognized Tax Benefits [Roll Forward]
Schedule of reconciliation of unrecognized tax benefits activity [Roll Forward]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Assets, Current
Total current assets
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Expected volatility
Measurement Input, Common Stock Market Price [Member]
Measurement Input, Common Stock Market Price.
Common Stock Market Price [Member]
Issue and sale of share
Issue and sale of share
Sale and issuance of common stock, net (in shares)
Unrecognized Tax Benefits
Unrecognized Tax Benefits – Ending
Unrecognized Tax Benefits – Beginning
Net operating loss carryforward.
Net Operating Loss Carryforward
Net operating losses
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Change in valuation allowance
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Stock option vesting period
Lessee, Operating Lease, Existence of Option to Extend [true false]
Lessee, operating lease, existence of option to extend [true false]
Distribution Type [Axis]
Entity Filer Category
Entity Filer Category
Deferred Tax Assets, Property, Plant and Equipment
Property and equipment, net
Effective Income Tax Rate Reconciliation Mark to Market
Effective income tax rate reconciliation mark to market.
Mark to market
Twenty twenty purchase agreement.
Twenty Twenty Purchase Agreement [Member]
2020 Purchase Agreement [Member]
Asset Acquisition [Domain]
Deferred grant liability
Increase Decrease In Deferred Grant Liability
Increase (decrease) in deferred grant liability.
Net Income (Loss) Available to Common Stockholders, Diluted
Net loss attributable to common stockholders - diluted
Fair Value of Warrant Liability Reclassified to Equity
Fair Value of Warrant Liability Reclassified to Equity
Fair value of warrant liability reclassified to equity
Amount To Be Received As Award For Research And Development
Amount to be received as award for research and development.
Amount to be received as award for research and development
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Organization and Operations
Composition of Certain Financial Statement Captions [Abstract]
Composition Of Certain Financial Statement Captions [Abstract]
Current Fiscal Year End Date
Current Fiscal Year End Date
Distribution agreement member.
Distribution Agreement [Member]
2020 Distribution Agreement [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: amount representing interest
Warrant Issuance Costs
Warrant issuance costs.
Warrant issuance costs
2020 Repurchase Agreement.
Twenty Twenty Repurchase Agreement [Member]
2020 Repurchase Agreement [Member]
Private Placement and Prefunded Warrant [Member]
Private Placement and Prefunded Warrant[Member]
Private Placement and Prefunded Warrant.
Share-Based Payment Arrangement, Noncash Expense
Share-based compensation expense
Share-Based Payment Arrangement, Noncash Expense, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Balance as of December 31, 2023
Balance as of December 31, 2024
Related and Nonrelated Parties [Axis]
Related Party
Debt Instrument, Fee Amount
Fees amount associated with loan
Entity Registrant Name
Entity Registrant Name
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
Compensation and Employee Benefit Plans [Text Block]
Employee Benefit Plan
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Earnings Per Share [Text Block]
Loss per Share
Debt Instrument, Maturity Date
Maturity date
Entity Emerging Growth Company
Entity Emerging Growth Company
Recorded Unconditional Purchase Obligation [Table]
Recorded Unconditional Purchase Obligation [Table]
Money Market [Member]
Money Market Funds [Member]
Payments to Acquire Intangible Assets
Purchases of intangible assets
Other Liabilities, Current
Other current liabilities
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average shares of common stock outstanding - basic
Weighted average number of shares of common stock outstanding - basic
Number of maximum common shares can be resale.
Number of Maximum Common Shares Can Be Resale
Number of maximum common shares can be resale
SEC Schedule, 12-09, Schedule of Valuation and Qualifying Accounts Disclosure [Text Block]
Financial Statement Schedules
Distribution Type [Domain]
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Operating Leases
Litigation Case [Axis]
Litigation Case
Common Stock, Shares Authorized
Common stock, shares authorized (in shares)
Interest Payable, Current
Accrued interest
Property, Plant and Equipment, Useful Life
Useful lives of the assets
Term Loan Outstanding
Schedule of Long-Term Debt Instruments [Table Text Block]
Gross proceeds from sale of common stock
Proceeds from Issuance of Common Stock
Proceeds from sale of common stock, net
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Debt Disclosure [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Expected Dividend
Dividend yield assumed
Documents Incorporated by Reference [Text Block]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted (in dollars per share)
Amortization of Intangible Assets
Amortization
Accumulated Amortization
Financial Instrument [Axis]
Financial Instrument
Balance as of December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to net operating loss expiration.
Effective Income Tax Rate Reconciliation Net Operating Loss Expiration
NOLs expiring and adjustments to NOL
NOLs expiring and adjustments to NOL
Earnings Per Share, Policy [Policy Text Block]
Loss Per Share
Cash payment information.
Cash Payment Information [Abstract]
Cash payment information:
Debt, Policy [Policy Text Block]
Deferred Financing Costs and Other Debt-Related Costs
General and Administrative Expense [Member]
General and Administrative [Member]
Impairment, Long-Lived Asset, Held-for-Use
Impairment loss
Impairment, Long-Lived Asset, Held-for-Use, Total
Stock-based Compensation [Abstract]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
At the market offering program.
At The Market Offering Program [Member]
At The Market Offering Program [Member]
Proceeds from Issuance of Warrants
Proceeds from issuance of warrants
Cybersecurity Risk Role of Management [Text Block]
Treasury stock (at cost, 78,559 shars as of December 31, 2023)
Treasury Stock, Common, Value
Treasury stock (at cost, 258,425 and 78,559 shares as of December 31, 2024 and 2023, respectively)
Accounting Policies [Abstract]
Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract]
purchase price of share.
Purchase price of share
Long-Term Line of Credit
Long-Term Line of Credit, Total
Line of credit
Income Tax Disclosure [Abstract]
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Gross increase – current-period tax positions
Stockholders' equity (deficit):
Equity, Attributable to Parent [Abstract]
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental schedule of non-cash investing and financing activities:
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Percent
Other, net
Statement [Table]
Statement [Table]
Segment Reporting, Policy [Policy Text Block]
Segment Information
Property, Plant and Equipment [Table Text Block]
Property and Equipment, Net
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest at December 31, 2024
Subsequent Event [Table]
Subsequent Event [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted Average Exercise Price [Roll Forward]
Preferred Stock, Shares Authorized
Preferred stock, shares authorized (in shares)
Fair value loss on warrant liability
Change in fair value of warrants
Change in fair value of warrants
Change in fair value of warrants
Entity File Number
Entity File Number
Segment Reporting Disclosure [Text Block]
Segment Information
Net decrease in cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Revenue from Contract with Customer [Abstract]
Securities Purchase And Exchange Agreement [Member]
Securities purchase and exchange agreement.
Securities Purchase and Exchange Agreement [Member]
Earnings Per Share [Abstract]
Warrants and Rights Outstanding, Term
Warrant liability, Expected term
Biocept Agreement [Member]
Biocept Agreement [Member]
Biocept Agreement.
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Share based compensation
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Income tax benefit at state statutory rate
Income tax benefit at state statutory rate
Contractual Obligation, Fiscal Year Maturity [Table Text Block]
Future Payments under Obligation
Income Tax Examination, Penalties and Interest Expense
Interest or penalties related to income tax matters
Income Tax Examination, Penalties and Interest Expense, Total
Statement of Financial Position [Abstract]
Operating Income (Loss)
Operating loss
Accrued license payable.
Accrued License Payable
Accrued payments due to NanoTx
Accrued Bonuses, Current
Accrued payroll and bonus
Entity Shell Company
Entity Shell Company
Line of Credit Facility [Table]
Accrued Professional Fees, Current
Accrued professional fees
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Summary of Key Inputs Used in Valuation of Liability Classified Warrants
Entity Tax Identification Number
Entity Tax Identification Number
Assets [Abstract]
Assets
Class of Warrant or Right [Domain]
Class of Warrant or Right
Fair Value of Financial Instruments, Policy [Policy Text Block]
Financial Instruments
Entity Current Reporting Status
Entity Current Reporting Status
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable at December 31, 2024
Asset Acquisition [Text Block]
Biocept Asset Acquisitions
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Accounts Payable and Accrued Expenses
Subsequent Events [Abstract]
Grant Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Biocept Asset Acquisitions [Member]
Biocept asset acquisitions.
Biocept Asset Acquisitions [Member]
Document Fiscal Year Focus
Document Fiscal Year Focus
Gross proceeds from issuance of common stock.
Gross Proceeds from Issuance of Common Stock
Aggregate gross proceeds from sales of common stock
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value; 5,000,000 shares authorized; 1,952 shares issued and outstanding as of December 31, 2024 and 2023
Repayments of Long-Term Debt
Principal payments of long-term obligations
Repayments of Long-Term Debt, Total
Finite-Lived Intangible Assets, Accumulated Amortization
Accumulated Amortization
Purchase of treasury stock
Purchase of treasury stock
Treasury Stock, Value, Acquired, Cost Method
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Unrecognized Tax Benefits Activity
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash and cash equivalents at end of period
Cash and cash equivalents at beginning of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Department of Defense Award [Member]
Department of defense award.
Proceeds from sale of common stock, net of offering costs of $0.2 million
Proceeds From Issuance Of Common Stock Net of Offering Costs
Proceeds from issuance of common stock net of offering costs.
City Area Code
City Area Code
Warrants and Rights Outstanding, Measurement Input
Warrant liability, Measurement input
Liabilities, Current
Total current liabilities
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Income tax expense (benefit) at federal statutory rate
Goodwill and Intangible Assets, Policy [Policy Text Block]
Goodwill
Rule 10b51 Arr Modified Flag
Rule 10b51 Arr Modified Flag.
Rule 10b51 Arr Modified Flag
Maximum grant amount to be received as per grant contract.
Maximum Grant Amount to be Received as per Grant Contract
Maximum grant amount to be received as per grant contract
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Local Phone Number
Local Phone Number
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Leasehold Improvements, Gross
Leasehold improvements
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Total
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Percentage of matching contribution for employee contributions
Income Tax Jurisdiction [Axis]
Income Tax Authority
Grants Receivable
Grant revenue receivable
Income Tax, Policy [Policy Text Block]
Income Taxes
Fractional adjustment
Fractional Adjustment of Common Stock
Fractional adjustment of common stock.
Commitments and Contingencies Disclosure [Abstract]
Shares issued
Shares, Issued
Remaining common stock issued and sold (in shares)
Treasury stock
Treasury Stock, Value
Treasury Stock, Value, Total
Convertible Preferred Stock [Member]
Debt Securities, Available-for-Sale, Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost, Total
Debt Securities, available-for-sale, amortized cost and fair value
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Deferred Tax Assets and Liabilities
Percentage of commission on gross proceeds from sale of common stock.
Percentage of Commission on Gross Proceeds from Sale of Common Stock
Percentage of commission on gross proceeds from sale of common stock
Operating Lease, Liability, Current
Operating lease liability
Operating lease liabilities, current
Less: current portion
In Process Research and Development [Member]
Income Tax Jurisdiction [Domain]
Income Tax Authority
Series B Warrant [Member]
Series B Warrant.
Debt Instrument, Interest Rate, Stated Percentage
Interest Rate
Personnel Related Expenses [Member]
Personnel Related Expenses [Member]
Personnel Related Expenses [Member]
Retained Earnings [Member]
Accumulated Deficit [Member]
Amortization of Debt Issuance Costs and Discounts
Amortization of deferred financing costs and debt discount
Amortization of Debt Issuance Costs and Discounts, Total
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Earnings Per Share, Basic [Abstract]
Basic and diluted net loss per share of common stock calculation:
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
In process research and development acquired
Cash Paid For I P R D Asset Acquired In An Asset Acquisition
Cash paid for IPRD asset acquired in an asset acquisition.
Amendment and Restatements May 2024 Private Placement [Member]
Amendment and restatements May 2024 private placement.
Document Transition Report
Document Transition Report
Stock Repurchase Program Authorized Dollar Amount
Authorized amount of repurchase of stock
Lessee, Operating Lease, Liability, to be Paid, Year Two
2026
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Subscription Agreement [Member]
Subscription Agreement [Member]
Number of Reporting Units
Number of reporting units
Unpaid Offering Costs.
Unpaid Offering Costs
Unpaid offering cost
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Accrued expenses
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration Risk
Auditor Firm ID
Auditor Firm ID
Minimum [Member]
Minimum [Member]
Common Stock [Member]
Common Stock [Member]
Other assets
Other assets
Increase (Decrease) in Other Noncurrent Assets
Reduction in the carrying amount of operating lease right-of-use assets
Operating Lease, Right-of-Use Asset, Periodic Reduction
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Securities Purchase Agreement [Member]
Securities purchase agreement.
Income taxes.
Income Taxes [Line Items]
Income Taxes [Line Items]
Statement of Income Location, Balance [Domain]
Income Statement Location
Lessee, Operating Lease, Liability, to be Paid, Year One
2025
Other Assets, Noncurrent
Other assets
Series A Warrant [Member]
Series A Warrant.
Other Prepaid Expense, Current
Prepaid services
Accounts Payable and Accrued Liabilities [Abstract]
Accounts Payable and Accrued Expenses [Abstract]
Grant Receivable
Grant receivable.
Grant receivable
Sales agreement.
Sales Agreement [Member]
Sales Agreement [Member]
Single-Stock Future [Member]
Single Regular Purchase [Member]
Share Repurchase Program, Remaining Authorized, Amount
Remained authorized amount for repurchase
Other Assets, Current
Other current assets
Total other current assets
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Disaggregation of Revenue [Line Items]
Non-Cash Financing Expense
Non-cash financing expense.
Non-cash financing expenses
2025
Finite-Lived Intangible Asset, Expected Amortization, Year One
Debt Securities, Available-for-Sale, Premium on Purchased Options [Policy Text Block]
Available-for-Sale Securities
Segment Reporting, Expense Information Used by CODM, Description
Revenue, Product and Service [Extensible Enumeration]
Components of Deferred Tax Assets and Liabilities [Abstract]
Portions of the deferred tax assets and deferred tax liabilities [Abstract]
Common Stock, Value, Issued
Voting stock, value
Common stock, $0.001 par value; 100,000,000 shares authorized; 6,154,758 shares issued and 5,896,333 outstanding as of December 31, 2024, 4,522,656 shares issued and 4,444,097 outstanding as of December 31, 2023, respectively
Asset Acquisition [Table]
Outstanding balance
Line of Credit, Current
Line of credit
Payments for Royalties
License fee payment in cash
Investment Income, Interest
Interest income
Future Amortization Expense on Intangible Assets
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Prepaid Insurance
Prepaid insurance
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents
Number Of Preferred Stock Shares Exercised.
Number Of Preferred Stock Shares Exercised
Number of preferred stock, shares converted
Summary of Financial Assets Measured at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Other Intangible Assets, Net
Intangible assets, net
Debt Instrument, Offering Date
Origination date
Property, Plant and Equipment, Net [Abstract]
Property and Equipment, net [Abstract]
Percentage of credit facility cannot exceed collateralized marketable securities
Percentage of Credit Facility Cannot Exceed Collateralized Marketable Securities
Percentage of credit facility cannot exceed collateralized marketable securities.
Lease liability
Operating Lease, Liability
Present value of obligations under leases
Effective Income Tax Rate Reconciliation Warrants
Effective income tax rate reconciliation warrants.
Warrants
Warrants
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Deferred tax assets related to NOL carryforwards
Commitments and Contingencies
Commitments and contingencies (Note 7)
Restricted beneficial ownership level result of exercise of warrant to receive pre-funded warrant
Restricted Beneficial Ownership Level Result of Exercise of Warrant To Receive Pre-funded Warrant
Restricted beneficial ownership level result of exercise of warrant to receive pre-funded warrant.
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average shares of common stock - diluted
Weighted average number of shares of common stock outstanding - diluted
Non Rule 10b51 Arr Modified Flag
Non rule 10b51 arr modified flag.
Non Rule 10b51 Arr Modified Flag
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Segment Expenses
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Manufacturing Agreement with SpectronRX [Member]
Manufacturing Agreement with SpectronRX.
Lessee, Operating Lease, Renewal Term
Lessee, operating lease, renewal term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest at December 31, 2024 (in shares)
Lessee, Operating Lease, Liability, to be Paid
Minimum lease payment
Total minimum lease payments
Other Deferred Costs, Net
Other Deferred Costs, Net, Total
Deferred costs (Note 7)
Cybersecurity Risk Management Third Party Engaged [Flag]
The gross amount of office and computer equipment cost as of the balance sheet date.
Office And Computer Equipment Gross
Office and computer equipment
Finance Lease, Liability
Finance lease obligation -- current
Finance Lease, Liability, Total
Entity Small Business
Entity Small Business
Segment Reporting Information [Line Items]
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Debt Instrument, Basis Spread on Variable Rate
Basis variable rate
Debt Disclosure [Text Block]
Term Loan Obligations
Pre-Funded Warrants [Member]
Pre-funded warrants member.
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Federal tax carry forward
Issuance of common stock for in process research and development (in shares)
Stock Issued During Period, Shares, Issued for Services
Revenue recognized
Revenues, Total
Revenue
US Treasury Securities [Member]
Treasury Bills [Member]
Investments, Fair Value Disclosure
Investments, Fair Value Disclosure, Total
Investments
Purchase of treasury stock (in Shares)
Purchase of treasury stock (in Shares)
Treasury Stock, Shares, Acquired
Line of Credit Facility [Abstract]
Credit Facility [Axis]
Contractual Obligation
Contractual obligation
Total
Total debt obligations, including final payment fee (Face Value)
Exchange [Member]
Exchange.
Accretion of discount on short-term investments
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of discount on short-term investments
Series A Warrant and Series B Warrant [Member]
Series a warrant and series b warrant.
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Internal Revenue Service (IRS) [Member]
Internal Revenue Code [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Balance as of December 31, 2023 (in dollars per share)
Balance as of December 31, 2024 (in dollars per share)
Cancer prevention and research institute of texas contract.
Cancer Prevention And Research Institute Of Texas Contract [Member]
CPRIT Contract [Member]
State and Local Jurisdiction [Member]
State [Member]
Right-of-use assets acquired by assuming operating lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Line of Credit Facility, Commitment Fee Percentage
Applicable fees
Measurement Frequency [Domain]
Measurement Frequency [Domain]
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Stock based compensation 2020 equity incentive plan.
Stock Based Compensation2020 Equity Incentive Plan [Member]
2020 Plan [Member]
Net income from continuing operations
Income (Loss) from Continuing Operations, Net of Tax, Attributable to Parent
Income (Loss) from Continuing Operations, Net of Tax, Attributable to Parent, Total
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, weighted average remaining term
Subsequent Events [Text Block]
Subsequent Events
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Change in accounting principle, accounting standards update, immaterial effect
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Debt Instrument Floor Rate
Debt instrument floor rate.
Debt instrument floor rate
Accounts Payable and Accrued Liabilities, Current
Accounts payable and accrued expenses
Accounts payable and accrued expenses, Total