Entity Address, City or Town
Entity Address, City or Town
Period for regain compliance.
Period For Regain Compliance
Period for regain compliance
Other Current Assets
Schedule of Other Current Assets [Table Text Block]
Reconciliation of Total Income Tax Provision
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Fair Value Disclosures [Abstract]
Income Tax Contingency [Abstract]
Income Tax Contingency [Abstract]
Income tax contingency.
Earnings Per Share [Abstract]
Change in fair value of liability instruments
Liabilities, Fair Value Adjustment
Federal [Member]
Domestic Tax Authority [Member]
Sale of common stock, net
Issuance of common stock for exercise of warrants
Stock Issued During Period, Value, New Issues
Proceeds from exercise of warrants
Proceeds From Warrant Exercises1
Proceeds from warrant exercises.
Recorded Unconditional Purchase Obligation by Category of Item Purchased
Recorded Unconditional Purchase Obligation by Category of Item Purchased [Axis]
Research and Development
Research and Development Expense, Policy [Policy Text Block]
Cash flows from financing activities:
Net Cash Provided by (Used in) Financing Activities [Abstract]
Dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Amendment Flag
Amendment Flag
Subsequent Event Type
Subsequent Event Type [Domain]
Litigation Case
Litigation Case [Domain]
Goodwill, Ending Balance
Goodwill, Beginning Balance
Goodwill, Total
Goodwill
Goodwill
Office Laboratory and Storage Space [Member]
Office Laboratory And Storage Space [Member]
Office, laboratory and storage space.
Operating
Operating lease right-use-of assets
Operating Lease, Right-of-Use Asset
State tax credit carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
Debt Instrument [Table]
Schedule of Long-Term Debt Instruments [Table]
Less: amount representing interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Statement [Table]
Statement [Table]
Operating lease liabilities. noncurrent
Noncurrent operating lease liability
Operating Lease, Liability, Noncurrent
Interest expense on lease liabilities
Finance Lease, Interest Expense
Single Regular Purchase [Member]
Single-Stock Future [Member]
2022 Distribution Agreement [Member]
Two Thousand Twenty Two Distribution Agreement [Member]
Two thousand twenty two distribution agreement.
Summary of Lease Liabilities and Right-of-Use Assets
Schedule Of Right Of Use Assets And Lease Liabilities Table [Text Block]
Schedule of right of use assets and lease liabilities.
Change in accounting principle, accounting standards update, immaterial effect [true false]
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Operating cash used for operating leases
Operating Lease, Payments
Number of operating segment
Number of Operating Segments
LIBOR [Member]
London Interbank Offered Rate (LIBOR) [Member]
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding
Number of shares reserved for issuance and sale
Increased in the total number of shares of common stock reserved for issuance
Common Stock, Capital Shares Reserved for Future Issuance
Auditor Firm ID
Auditor Firm ID
Lorem Vascular Pte Ltd [Member]
Lorem Vascular Pte Ltd [Member]
Lorem Vascular, Pte. Ltd.
Piramal Pharma Solutions, Inc. [Member]
Piramal Pharma Solutions Inc [Member]
Piramal pharma solutions inc.
Remaining common stock issued and sold (in shares)
Shares, Issued
Income Tax Authority
Income Tax Authority [Domain]
Deferred Tax Assets, Tax Credit Carryforwards, Total
Income tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards
ASU 2019-12 [Member]
Accounting Standards Update 2019-12 [Member]
Product and Service
Product and Service [Axis]
Cash paid during period for:
Cash paid during period for:
Cash Paid During Period For [Abstract]
Liability for uncertain tax positions
Liability for Uncertainty in Income Taxes, Current
Deferred Financing Costs and Other Debt-Related Costs
Debt, Policy [Policy Text Block]
2018 Rights Offering [Member]
Two Thousand Eighteen Rights Offering [Member]
Two thousand eighteen rights offering.
Litigation settlement, expense
Litigation Settlement, Expense
2022 Purchase Agreement [Member]
Two Thousand and Twenty Two Purchase Agreement [Member]
Two thousand and twenty two purchase agreement.
Disposal Group Classification
Disposal Group Classification [Domain]
Operating lease, weighted average remaining term
Operating Lease, Weighted Average Remaining Lease Term
Series A 3.6% Convertible preferred stock eliminated date
Preferred Stock Dividend Rate Percentage Eliminated Date
Preferred stock dividend rate percentage eliminated date.
Total liabilities and stockholders’ equity
Liabilities and Equity
Plan Name
Plan Name [Domain]
Other current liabilities
Other Liabilities, Current
Change in fair value of liability instruments
Fair Value Adjustment of Warrants
Percentage of grant proceeds with interest not exceed annually
Percentage Of Grant Proceeds With Interest Not Exceed Annually
Percentage of grant proceeds with interest not exceed annually.
Change in accounting principle, accounting standards update, adopted [true false]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Vested and expected to vest at December 31, 2021 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Organization and Operations
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Sale of Stock
Sale of Stock [Domain]
Total current liabilities
Liabilities, Current
Tax loss carryforwards
Operating Loss Carryforwards
2025
Lessee, Operating Lease, Liability, to be Paid, Year Three
Interest Expense, Total
Interest expense
Interest expense
Interest Expense
Income Taxes
Income Tax, Policy [Policy Text Block]
UTHSA License Agreement [Member]
U T H S A License Agreement [Member]
UTHSA License Agreement.
Remaining availability under financing facility
Common Stock Sales Available For Issuance
Common stock, sales, available for issuance.
Valuation allowance
Deferred Tax Assets Valuation Allowances
Deferred tax assets valuation allowances.
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Net deferred tax assets (liability)
Deferred Tax Liabilities, Net
License Agreement [Abstract]
License agreement abstract.
Operating lease, weighted average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Finance lease expense:
Finance Lease Expense [Abstract]
Finance lease expense.
Term Loan [Member]
Term Loan [Member]
Second amendment to the amended and restated loan and security agreement.
Variable Rate
Variable Rate [Axis]
Entity Small Business
Entity Small Business
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock [Member]
Series A convertible preferred stock.
Interest Rate Floor [Member]
Interest Rate Floor [Member]
Investments
Investments [Domain]
Total current assets
Assets, Current
Diluted weighted average shares used in calculating net loss per share attributable to common stockholders
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Finance Lease, Liability, Total
Finance lease obligation -- current
Finance Lease, Liability
City Area Code
City Area Code
Face Value to Book Value Reconciliation
Schedule of Debt [Table Text Block]
Cancelled/forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Stock-based Compensation [Abstract]
Share-Based Payment Arrangement [Abstract]
September 2022 Distribution Agreement [Member]
September Two Thousand and Twenty Two Distribution Agreement [Member]
September two thousand and twenty two distribution agreement.
Total liabilities
Liabilities
Document Period End Date
Document Period End Date
Issuance costs paid in common stock
Payments of Stock Issuance Costs
Maximum value of shares to be issued under agreement
Maximum Value of Shares to be Issued Under Agreement
Maximum value of shares to be issued under agreement.
Services agreement.
Services Agreement [Member]
Services Agreement [Member]
Share based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Acquired In-Process Research and Development (IPR&D)
In Process Research and Development, Policy [Policy Text Block]
Resulting fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Lessee, operating lease, renewal term
Lessee, Operating Lease, Renewal Term
Statistical Measurement
Statistical Measurement [Axis]
Reconciliation of the total income tax provision tax rate [Abstract]
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Accrued R&D studies
Accrued Research And Development Studies
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development studies.
2015 Plan [Member]
Stock Based Compensation2015 Equity Incentive Plan1 [Member]
Stock based compensation 2015 equity incentive plan 1 member.
Total other current assets
Other current assets
Other Assets, Current
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Canaccord Genuity LLC [Member]
Canaccord Genuity LLC [Member]
Canaccord Genuity L L C [Member]
Canaccord Genuity LLC Member.
Related Party
Related Party [Axis]
Total assets
Assets
Charlottesville [Member]
Charlottesville [Member]
Charlottesville
Derivative Contract
Derivative Contract [Domain]
Conversion of Series B convertible preferred stock into common stock (in shares)
Stock Issued During Period, Shares, Conversion of Convertible Securities
Accrued vacation and compensation
Accrued Vacation And Compensation Current
Accrued vacation and compensation, current.
State [Member]
State and Local Jurisdiction [Member]
Return to provision
Effective Income Tax Rate Reconciliation Tax Return To Provision
Effective income tax rate reconciliation tax return to provision.
Long-Term Debt, Excluding Current Maturities, Total
Term loan obligation
Long-Term Debt, Excluding Current Maturities
Net loss per share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Schedule of Antidilutive Securities Excluded from Diluted Income (Loss) per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Net operating loss carryforwards, Expire date
Operating Loss Carryforwards Expiration Dates1
The expiration date of each operating loss carryforward included in total operating loss carryforwards, or the applicable range of such expiration dates.
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
License Agreements
License Agreement Disclosure [Text Block]
Disclosure of accounting policy for license agreement.
Document Fiscal Period Focus
Document Fiscal Period Focus
Outstanding Stock Options [Member]
Options [Member]
Options.
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Preferred stock, $0.001 par value; 5,000,000 shares authorized; 1,95 shares issued and outstanding as of December 31, 2022 and 2021
Preferred Stock, Value, Issued
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Share-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Interest income
Investment Income, Interest
Present value of obligations under leases
Operating Lease, Liability
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Other
Other
Other.
Statement of Financial Position [Abstract]
Disposal Group Classification
Disposal Group Classification [Axis]
Entity File Number
Securities Act File Number
Statement of Cash Flows [Abstract]
Number of securities called by warrant or right
Number of shares callable by warrants (in shares)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Lincoln Park Capital Fund, LLC [Member]
Lincoln Park Capital Fund L L C [Member]
Lincoln park capital fund, LLC.
Geographical
Geographical [Domain]
Statistical Measurement
Statistical Measurement [Domain]
Statement of Stockholders' Equity [Abstract]
Sale of Stock
Sale of Stock [Axis]
Non-cash amortization
Amortization of Debt Discount (Premium)
Accrued payroll and bonus
Accrued Bonuses, Current
Auditor Location
Auditor Location
Class of Stock
Class of Stock [Domain]
Loan and Security Agreement [Member]
Loan And Security Agreement [Member]
Loan and security agreement.
Grant Receivable and Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Legal Entity
Legal Entity [Axis]
Summary of Lease Costs
Lease, Cost [Table Text Block]
Stockholders' Equity Note [Abstract]
Subsequent Events [Abstract]
Period exercisable from the date of issuance
Period Exercisable From The Date Of Issuance
Refers to the period exercisable from the date of issuance.
Consecutive business days.
Consecutive Business Days
Consecutive business days
Exercisable at December 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Proceeds from sale of common stock, net
Proceeds from sale of common stock
Proceeds from Issuance of Common Stock
2023
Contractual Obligation, to be Paid, Year One
Research and development credits, overstated
Deferred Tax Assets, Tax Credit Carryforwards, Research
Contract effective date
Contract Effective Date
Contract effective date.
Property and Equipment, net
Property, Plant and Equipment [Table Text Block]
Grant [Member]
Grant [Member]
Grant Revenue
Revenue from Contract with Customer [Text Block]
Concentration Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
Issuance of common stock for exercise of warrants (in shares)
Stock Issued During Period Shares Warrants Exercise Shares
Stock issued during period shares warrants exercise(shares).
Composition of Certain Financial Statement Captions
Supplemental Balance Sheet Disclosures [Text Block]
San Antonio, Texas [Member]
TEXAS
Basic weighted average shares used in calculating net loss per share attributable to common stockholders
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Sales order cost
Sales Order Cost
Sales order cost.
Income Taxes [Table]
Income Taxes [Table]
Income taxes.
General and Administrative [Member]
General and Administrative Expense [Member]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Current Fiscal Year End Date
Current Fiscal Year End Date
Investment Type
Investment Type [Axis]
Initial commitment shares
Initial Commitment Shares
Initial commitment shares.
Sale of the Japanese Subsidiary and Certain Assets [Member]
Sale Of Japanese Subsidiary And Certain Assets [Member]
Sale of the japanese subsidiary and certain assets.
Depreciation, Total
Depreciation expense
Depreciation
Financial Instruments
Financial Instruments [Domain]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Number of stock repurchased
Stock Repurchased During Period, Shares
Other assets
Other Assets, Noncurrent
Entity Address, Address Line One
Entity Address, Address Line One
Repayments of Long-Term Debt, Total
Principal payments of long-term obligations
Repayments of Long-Term Debt
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Amount of lessee's undiscounted obligation for lease payments for operating lease, due after fourth fiscal year following latest fiscal year.
Commitment Fee [Member]
Commitment Fee [Member]
Commitment fee.
Document Annual Report
Document Annual Report
Supplemental disclosure of cash flows information:
Supplemental Cash Flow Information [Abstract]
Deferred tax assets [Abstract]
Components of Deferred Tax Assets [Abstract]
Operating leases, expiration date
Lease Expiration Date
Impairment
Property, Plant and Equipment, Impairment [Policy Text Block]
Income Tax Expense (Benefit), Total
Provision or benefit for income taxes
Income Tax Expense (Benefit)
Contract termination date
Contract Termination Date
Contract termination date.
Summary of Future Minimum Annual Lease Payments under Operating and Financing Leases
Schedule Of Operating And Financing Lease Liability Maturity Table [Text Block]
Schedule of operating and financing lease liability maturity.
Change in operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Portions of the deferred tax assets and deferred tax liabilities [Abstract]
Components of Deferred Tax Assets and Liabilities [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued
Total obligation
Long-Term Debt and Lease Obligation, Including Current Maturities
Share based compensation
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Income Tax Disclosure [Abstract]
Change in accounting principle, accounting standards update, adoption date
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Common stock issued (in shares)
Sale of common stock, net (in shares)
Stock Issued During Period, Shares, New Issues
Total cash paid for amounts included in the measurement of lease liabilities
Cash Paid For Amounts Included In Measurement Of Lease Liabilities
Cash paid for amounts included in the measurement of lease liabilities.
Percentage of federal net operating losses used to offset of future taxable income
Percentage Of Net Operating Loss Carryforwards Available For Offsetting Against Future Taxable Income
Percentage of net operating loss carryforwards available for offsetting against future taxable income.
Number of reporting units
Number of Reporting Units
Share-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Grant funding term
Grant Funding Term
Grant funding term.
Auditor Name
Auditor Name
Cancelled/forfeited (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Other long-term liabilities
Increase (Decrease) in Other Noncurrent Liabilities
Annual increase in lease rate
Annual Increase In Lease Rate
Annual increase in lease rate
Operating loss
Operating Income (Loss)
Interest Rate
Debt Instrument, Interest Rate, Stated Percentage
Lessee, operating lease, option to extend
Lessee, Operating Lease, Option to Extend
Related Party
Related Party [Domain]
In process research and development acquired
Research and Development in Process
Accrued professional fees
Accrued Professional Fees, Current
Recorded Unconditional Purchase Obligation [Table]
Recorded Unconditional Purchase Obligation [Table]
Class of Warrant or Right
Class of Warrant or Right [Domain]
Entity Filer Category
Entity Filer Category
Leasehold improvements
Leasehold Improvements, Gross
Total operating expenses
Operating Expenses
Entity Current Reporting Status
Entity Current Reporting Status
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Accounts Payable and Accrued Expenses
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Lease commencement date
Lease Commencement Date
Lease commencement date.
Asset Impairment Charges, Total
Impairment charges
Asset Impairment Charges
Stockholders' Equity
Stockholders' Equity Note Disclosure [Text Block]
Total stockholders’ equity
Balance
Balance
Stockholders' Equity Attributable to Parent
Representative Warrants [Member]
Representative Series U Warrant [Member]
Representative Series U Warrant.
Initial commitment fee paid in cash
Initial Commitment Fee
Initial commitment fee.
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location
Income Statement Location [Axis]
Voting stock, value
Common stock, $0.001 par value; 100,000,000 shares authorized; 33,601,373and 15,510,025 shares issued and outstanding as of December 31, 2022 and 2021, respectively
Common Stock, Value, Issued
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Reimburse of fee and disbursements expenses
Aggregate Expense Including Fee and Disbursement Expenses
Aggregate expense including fee and disbursement expenses.
Equity Components
Equity Components [Axis]
Warrant expiration date
Class Of Warrant Or Right Expiration Date
The date that the warrant or right expires.
Accounting Standards Update
Accounting Standards Update [Domain]
Income Tax Examination, Penalties and Interest Expense, Total
Interest or penalties related to income tax matters
Income Tax Examination, Penalties and Interest Expense
Cash and cash equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
License fee payment in cash
Payments for Royalties
Date from which warrants are exercisable
Class of Warrant or Right, Date from which Warrants or Rights Exercisable
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Entity Emerging Growth Company
Entity Emerging Growth Company
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Summary of significant accounting policies.
Operating expenses:
Operating Expenses [Abstract]
Property and Equipment, net [Abstract]
Property, Plant and Equipment, Net [Abstract]
Compensatory damages and operational
Compensatory Damages And Operational
Compensatory damages and operational.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Summary of significant accounting policies.
Cumulative change in ownership
Cumulative Change In Ownership
Refers to cumulative change in ownership in percentage.
Schedule Of Stock By Class [Table]
Schedule of Stock by Class [Table]
Expected term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Unconditional Purchase Obligation, Category of Goods or Services Acquired
Unconditional Purchase Obligation, Category of Goods or Services Acquired [Domain]
Nano Tx Licenses Agreement [Member]
Nano Tx Licenses Agreement [Member]
Nano Tx license agreement Member
Operating Leases
Lessee, Operating Lease, Liability, to be Paid [Abstract]
Percentage issuance of common stock
Percentage Issuance Of Common Stock
Percentage issuance of common stock.
Entity Voluntary Filers
Entity Voluntary Filers
Weighted Average Remaining Contractual Life (years) [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Operating leases expiry year
Operating Leases Expiry Year
Operating leases, expiry year.
Retirement Benefits [Abstract]
Document Transition Report
Document Transition Report
Total other expense
Nonoperating Income (Expense)
Period of net operating loss and R&D tax credit carry forwards to offset future taxable income
Net Operating Loss And Research And Development Tax Credit Carry Forwards To Offset Future Taxable Income Period
Refers to the period of net operating loss and R&D tax credit carry forwards to offset future taxable income.
Depreciation, Depletion and Amortization, Total
Depreciation and amortization
Depreciation, Depletion and Amortization
Impairment, Long-Lived Asset, Held-for-Use, Total
Impairment loss
Impairment, Long-Lived Asset, Held-for-Use
Percentage of non-dilutive monetary awards required to pay
Percentage of Non-dilutive Monetary awards Required to Pay
Percentage of non-dilutive monetary awards required to pay.
Sale of Stock, Price Per Share
Sale of Stock, Price Per Share
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Series C Convertible Preferred Stock [Member]
Series C Convertible Preferred Stock [Member]
Series C convertible preferred stock.
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Property and equipment, principally due to differences in depreciation
Deferred Tax Assets, Property, Plant and Equipment
Pre-clinical Research Study Obligations [Member]
Pre Clinical Research Study Obligations [Member]
Contractual obligation to provide funding of research and development costs over periods that initially exceed one year or the normal operating cycle, if longer.
Period for material changes of liability for uncertain tax benefits
Period For Material Changes Of Liability For Uncertain Tax Benefits
Refers to period for material changes of liability for uncertain tax benefits.
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Debt Instrument, Periodic Payment, Total
Current Monthly Payment
Debt Instrument, Periodic Payment
Fair Value Measurements
Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]
Less: current portion
Operating lease liabilities, current
Operating lease liability
Operating Lease, Liability, Current
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Convertible preferred stock
Preferred Stock, Dividend Rate, Percentage
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Series B convertible preferred stock.
Deferred tax assets related to NOL carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Entity Registrant Name
Entity Registrant Name
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Loss per Share
Earnings Per Share [Text Block]
Weighted-average Assumptions
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Class of Stock
Class of Stock [Axis]
Maturity date
Debt Instrument, Maturity Date
Revenue
Revenues recognized
Revenues, Total
Share-Based Payment Arrangement, Noncash Expense, Total
Share-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
January 2022 Distribution Agreement [Member]
January Two Thousand and Twenty Two Distribution Agreement [Member]
January two thousand and twenty two distribution agreement.
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Depreciation of right-of-use assets
Finance Lease, Right-of-Use Asset, Amortization
Vested and expected to vest at December 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Debt Instrument, Unamortized Discount, Total
Less: Debt discount
Debt Instrument, Unamortized Discount
Statement [Line Items]
Statement [Line Items]
Percentage of aggregate amount of proceeds awarded under CPRIT grant
Percentage Of Aggregate Amount Of Proceeds Awarded Under CPRIT Grant
Percentage of aggregate amount of proceeds awarded under CPRIT grant.
Rent expense
Operating Lease, Expense
Title of 12(b) Security
Title of 12(b) Security
Closing bid price for common stock had fallen.
Closing Bid Price For Common Stock Had Fallen Below
Closing bid price for common stock had fallen below
Overstatement of deferred tax assets
Overstatement of Deferred Tax Assets
Overstatement of deferred tax assets.
Common Stock [Member]
Common Stock [Member]
Stock option contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Cash flows used in operating activities:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Equity Component
Equity Component [Domain]
Revenue recognized
Revenue from Contract with Customer, Excluding Assessed Tax
Entity Address, State or Province
Entity Address, State or Province
Total debt obligations, including final payment fee (Face Value)
Total
Contractual obligation
Contractual Obligation
Geographical
Geographical [Axis]
Warrant liability
Warrants and Rights Outstanding
Net increase (decrease) in cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Document Type
Document Type
Interest
Interest Paid, Excluding Capitalized Interest, Operating Activities
Federal tax carry forward
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Federal tax credit carryforward, Expiration date
Tax Credit Carryforward Expiration Date1
Expiration date of the tax credit carryforward.
CPRIT grant funding term, description
CPRIT Grant Funding Term
CPRIT grant funding term.
Entity Shell Company
Entity Shell Company
Class of warrant outstanding
Class of Warrant or Right, Outstanding
Financial Instruments
Fair Value of Financial Instruments, Policy [Policy Text Block]
Accrued expenses
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Long term debt outstanding threshold amount
Long Term Debt Outstanding Threshold Amount
Long Term Debt Outstanding Threshold Amount
Long term debt outstanding threshold amount.
Security Exchange Name
Security Exchange Name
Goodwill
Goodwill and Intangible Assets, Policy [Policy Text Block]
Master services agreement terms, Description
Master Services Agreement Terms Description
Master services agreement Terms description.
Revenue from Contract with Customer [Abstract]
Class of Stock [Line Items]
Class of Stock [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Net operating losses
Net Operating Loss Carryforward
Net operating loss carryforward.
Net cash used in operating activities
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Purchases of property and equipment and intangible assets
Payments To Acquire Property Plant And Equipment And Intangible Assets
Payments to acquire property plant and equipment and intangible assets.
Weighted average period for recognition of cost
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Balance as of December 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Fair Value By Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Commitments and Contingencies Disclosure [Abstract]
2020 Purchase Agreement [Member]
Twenty Twenty Purchase Agreement [Member]
Twenty twenty purchase agreement.
Future Payments under Obligation
Contractual Obligation, Fiscal Year Maturity [Table Text Block]
Operating lease expense
Operating Lease, Cost
Number of warrants exercised
Number Of Warrants Exercised
Number of warrants exercised
Unrecognized Tax Benefits Activity
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Composition Of Certain Financial Statement Captions [Abstract]
Composition of Certain Financial Statement Captions [Abstract]
Outstanding Warrants [Member]
Warrant [Member]
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Recently Issued Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding
2020 Distribution Agreement [Member]
Distribution Agreement [Member]
Distribution agreement member.
Term Loan Obligations
Debt Disclosure [Text Block]
Research credit
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
2020 Repurchase Agreement [Member]
Twenty Twenty Repurchase Agreement [Member]
2020 Repurchase Agreement.
Cash flows from (used in) investing activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Gross increase – current-period tax positions
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Commitments and contingencies (Note 6)
Commitments and Contingencies
Income Tax Authority, Name [Domain]
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Variable Rate
Variable Rate [Domain]
Minimum [Member]
Minimum [Member]
Income Tax Authority, Name [Axis]
Qualifying expenditures related to research
Qualifying Expenditures Related To Research And Development Expense
This represents contract with BARDA to develop a new countermeasure for thermal burns entitling the company to be reimbursed for qualifying expenditures.
Number of maximum common shares can be resale
Number of Maximum Common Shares Can Be Resale
Number of maximum common shares can be resale.
Exercisable at December 31, 2021 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Accounting Standards Update
Accounting Standards Update [Axis]
Common Class B [Member]
Common Class B [Member]
Medidata solutions, inc.
Medidata Solutions Inc [Member]
Medidata Solutions, Inc. [Member]
Debt Instrument
Debt Instrument [Axis]
Stockholders’ equity:
Stockholders' Equity Attributable to Parent [Abstract]
Income tax expense (benefit) at state statutory rate
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Entity Address, Address Line Two
Entity Address, Address Line Two
Amortization
Amortization of Intangible Assets
Subsequent Event [Member]
Subsequent Event [Member]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Total unamortized compensation cost related to outstanding unvested stock options and restricted stock awards
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Deferred tax assets (Total)
Deferred Tax Assets, Gross
NOLs expiring and adjustments to NOL
Effective Income Tax Rate Reconciliation Net Operating Loss Expiration
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to net operating loss expiration.
Cash payment information:
Cash Payment Information [Abstract]
Cash payment information.
Term loan obligation, current
Long-Term Debt, Current Maturities, Total
Term loan obligation, current
Long-Term Debt, Current Maturities
Issuance of common stock for exercise of warrants
Stock Issued During Period Shares Warrants Exercise
Stock issued during period shares warrants exercise.
Total minimum lease payments
Minimum lease payment
Lessee, Operating Lease, Liability, to be Paid
Gross decreases – tax positions in prior period
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
At The Market Offering Program [Member]
At The Market Offering Program [Member]
At the market offering program.
Change in state rate
Effective Income Tax Rate Reconciliation, Tax Settlement, State and Local, Percent
Lessee, operating lease, term of contract
Lessee, Operating Lease, Term of Contract
Intangible assets
Deferred Tax Assets, Goodwill and Intangible Assets
Entity Central Index Key
Entity Central Index Key
Other income (expense):
Other Income and Expenses [Abstract]
Increase (decrease) in valuation allowance
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Accounting Policies [Abstract]
Black-Scholes-Merton option valuation model based on weighted-average assumptions [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Litigation Case
Litigation Case [Axis]
Disaggregation of Revenue [Line Items]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Intangible assets, net
Other Intangible Assets, Net
Securities remaining and available for future issuances (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Share-based Compensation
Share-Based Payment Arrangement [Text Block]
2024
Contractual Obligation, to be Paid, Year Two
Fees amount associated with loan
Debt Instrument, Fee Amount
Prepaid insurance
Prepaid Insurance
Subsequent Event [Table]
Subsequent Event [Table]
General and Administrative Expense, Total
General and administrative
General and Administrative Expense
Amended expiration date
Debt Instrument Amended Expiration Date
Debt instrument amended expiration date.
Amortization of Debt Issuance Costs and Discounts, Total
Amortization of deferred financing costs and debt discount
Amortization of Debt Issuance Costs and Discounts
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Balance as of December 31, 2021 (in dollars per share)
Balance as of December 31, 2022 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Payment of finance lease liability
Financing cash used for financing leases
Finance Lease, Principal Payments
Research and Development [Member]
Research and Development Expense [Member]
Other current assets
Increase (Decrease) in Other Current Assets
Total lease expense
Lease, Cost
Warrant Liability
Standard Product Warranty, Policy [Policy Text Block]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Financial Statement Schedules
SEC Schedule, 12-09, Schedule of Valuation and Qualifying Accounts Disclosure [Text Block]
Accumulated Deficit [Member]
Retained Earnings [Member]
Reconciliation of Face Value to Book Value [Abstract]
Debt Instrument Reconciliation Of Face Value To Book Value [Abstract]
Reconciliation of Face Value to Book Value [Abstract]
Accrued payments due to NanoTx
Accrued License Payable
Accrued license payable.
Total income tax provision
Effective Income Tax Rate Reconciliation, Percent
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property and equipment, gross
Property, Plant and Equipment, Gross
Stock option vesting percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Additional Paid in Capital, Total
Additional paid-in capital
Additional Paid in Capital
Accounts Payable and Accrued Expenses [Abstract]
Accounts Payable and Accrued Liabilities [Abstract]
Entity Interactive Data Current
Entity Interactive Data Current
Entity Public Float
Entity Public Float
Vested and expected to vest at December 31, 2021 (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Aggregate gross proceeds from sales of common stock
Gross Proceeds from Issuance of Common Stock
Gross proceeds from issuance of common stock.
Stock Option Activity
Share-Based Payment Arrangement, Activity [Table Text Block]
Supplemental schedule of non-cash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
2023
Lessee, Operating Lease, Liability, to be Paid, Year One
Series U Warrants [Member]
Series U Warrants [Member]
Series U warrants member
Local Phone Number
Local Phone Number
Income tax expense (benefit) at federal statutory rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Unrecognized Tax Benefits – Beginning
Unrecognized Tax Benefits – Ending
Unrecognized Tax Benefits
Stock option vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Debt Disclosure [Abstract]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Reclassification of warrants liability to equity
Reclassifications Of Warrants Upon Exercise From Liability To Equity
Reclassifications of warrants upon exercise from liability to equity.
Exercisable at December 31, 2021
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Maximum grant amount to be received as per grant contract
Maximum Grant Amount to be Received as per Grant Contract
Maximum grant amount to be received as per grant contract.
Lessee, operating lease, existence of option to extend [true false]
Lessee, Operating Lease, Existence of Option to Extend [true false]
Common stock shares to be issued (in shares)
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Sales order term.
Sales Order Term
Sales order term
Deferred tax liabilities [Abstract]
Components of Deferred Tax Liabilities [Abstract]
Income Statement Location
Income Statement Location [Domain]
Balance (in shares)
Balance (in shares)
Shares, Outstanding
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Master service agreement date
Master Services Agreement Date
Master services agreement date.
Master services agreement initial term
Master Services Agreement Initial Term
Master services agreement initial term.
Percentage of commission on gross proceeds from sale of common stock
Percentage of Commission on Gross Proceeds from Sale of Common Stock
Percentage of commission on gross proceeds from sale of common stock.
Balance as of December 31, 2021 (in shares)
Balance as of December 31, 2022 (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Common Class A [Member]
Common Class A [Member]
Debt Instrument, Name
Debt Instrument, Name [Domain]
Document Fiscal Year Focus
Document Fiscal Year Focus
Other Current Assets [Abstract]
Prepaid Expense and Other Assets, Current [Abstract]
Class of Warrant or Right
Class of Warrant or Right [Axis]
Cash paid for IPRD asset acquired in an asset acquisition.
Cash Paid For I P R D Asset Acquired In An Asset Acquisition
In process research and development acquired
2024
Lessee, Operating Lease, Liability, to be Paid, Year Two
Net loss per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Prepaid services
Other Prepaid Expense, Current
Weighted Average Exercise Price [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Employee Benefit Plan
Compensation and Employee Benefit Plans [Text Block]
Assets
Assets [Abstract]
Additional details relating term loan that is outstanding [Abstract]
Additional Details Relating Term Loan That Is Outstanding [Abstract]
Additional details relating term loan that is outstanding [Abstract]
Net deferred tax asset
Deferred Tax Assets, Net
Deferred Tax Assets, Net, Total
Development [Member]
Development [Member]
Development.
Unpaid offering cost
Unpaid Offering Costs
Unpaid Offering Costs.
Term Loan Outstanding
Schedule of Long-Term Debt Instruments [Table Text Block]
Original loan amount
Debt Instrument, Face Amount
Financial Instrument
Financial Instrument [Axis]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Options [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Liabilities and Stockholders’ Equity
Liabilities and Equity [Abstract]
Income Taxes [Line Items]
Income Taxes [Line Items]
Income taxes.
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Deferred grant liability
Deferred Income, Noncurrent
Income Tax Authority
Income Tax Authority [Axis]
Total deferred tax assets, net of allowance
Deferred Tax Assets, Net of Valuation Allowance
Convertible Preferred Stock [Member]
Preferred Stock [Member]
Current assets:
Assets, Current [Abstract]
Warrant exercise price (in dollars per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Sales Agreement [Member]
Sales Agreement [Member]
Sales agreement.
Recorded Unconditional Purchase Obligation [Line Items]
Recorded Unconditional Purchase Obligation [Line Items]
Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Other
Deferred Tax Liabilities, Other
BARDA Contract [Member]
Barda Contract [Member]
Represents a contract to develop a new countermeasure for thermal burns with the U.S. Department of Health and Human Service's Biomedical Advanced Research and Development Authority (BARDA).
Discretionary or matching contributions
Defined Contribution Plan, Employer Discretionary Contribution Amount
Increases (decreases) in cash caused by changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Origination date
Debt Instrument, Offering Date
Lease expense:
Lease, Cost [Abstract]
Entity
Entity [Domain]
Cover [Abstract]
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Interest related to unrecognized tax benefits in interest expense and penalties
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Product and Service
Product and Service [Domain]
Schedule of reconciliation of unrecognized tax benefits activity [Roll Forward]
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Number of preferred stock, shares converted
Number Of Preferred Stock Shares Exercised
Number Of Preferred Stock Shares Exercised.
Current liabilities:
Liabilities, Current [Abstract]
Maximum [Member]
Maximum [Member]
Warrants expected term
Warrants and Rights Outstanding, Term
Future contractual principal and final fee payments on all debt [Abstract]
Contractual Obligation, Fiscal Year Maturity [Abstract]
Percentage of matching contribution for employee contributions
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Net cash used in investing activities
Net Cash Provided by (Used in) Investing Activities
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Office and computer equipment
Office And Computer Equipment Gross
The gross amount of office and computer equipment cost as of the balance sheet date.
Summary of Share-Based Compensation Recognized
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Accounts payable and accrued expenses, Total
Accounts payable and accrued expenses
Accounts Payable and Accrued Liabilities, Current
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Basis variable rate
Debt Instrument, Basis Spread on Variable Rate
Deferred Tax Liabilities, Gross, Total
Total deferred tax liability
Deferred Tax Liabilities, Gross
Cash Equivalents, at Carrying Value, Total
Cash equivalents investments with original maturities
Cash Equivalents, at Carrying Value
Stock options exercised
Stock Issued During Period, Value, Stock Options Exercised
Segment Information
Segment Reporting, Policy [Policy Text Block]
Debt instrument, covenant compliance
Debt Instrument, Covenant Compliance
Useful lives of the assets
Property, Plant and Equipment, Useful Life
Remaining Principal (Face Value)
Long-Term Debt, Gross
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Trading Symbol
Trading Symbol
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Common stock issued in payment for in process research and development
Common Stock Issued In Payment For In Process Research And Development
Common stock issued in payment for in process research and development.
SEC Schedule, 12-09, Valuation and Qualifying Accounts [Abstract]
Subsequent Event Type
Subsequent Event Type [Axis]
Other, net
Deferred Tax Assets, Other
Amortization of operating lease right-of-use assets
Operating Lease, Right-of-Use Asset, Amortization Expense
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Plan Name
Plan Name [Axis]
Interest rate
Debt Instrument Floating Interest Rate Percentage
Floating interest rate for funds borrowed, under the debt agreement.
CPRIT Contract [Member]
Cancer Prevention And Research Institute Of Texas Contract [Member]
Cancer prevention and research institute of texas contract.
Internal Revenue Code [Member]
Internal Revenue Service (IRS) [Member]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Loss on disposal of property and equipment
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
2020 Plan [Member]
Stock Based Compensation2020 Equity Incentive Plan [Member]
Stock based compensation 2020 equity incentive plan.
Dividend yield assumed
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Expected Dividend
Authorized amount of repurchase of stock
Stock Repurchase Program, Authorized Amount
Warrants issued, underwritten public offering, period.
Warrants Issued Underwritten Public Offering Period
Warrants issued, underwritten public offering, period
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Derivative Instrument
Derivative Instrument [Axis]
Research and development
Research and Development Expense (Excluding Acquired in Process Cost)
Granted (in dollars per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Dilutive common shares excluded from the calculations of diluted loss per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount