100000 - Document - Document and Entity Information
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100010 - Statement - BALANCE SHEETS
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100020 - Statement - BALANCE SHEETS (Parenthetical)
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100030 - Statement - STATEMENTS OF OPERATIONS
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100040 - Statement - STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)
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100050 - Statement - STATEMENTS OF CASH FLOWS
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995455 - Disclosure - Organization and Operations
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995485 - Disclosure - Loss per Share
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995495 - Disclosure - Composition of Certain Financial Statement Captions
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995505 - Disclosure - Commitments and Contingencies
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995515 - Disclosure - License Agreements
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995525 - Disclosure - Term Loan Obligations
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995535 - Disclosure - Grant Revenue
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995545 - Disclosure - Income Taxes
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995555 - Disclosure - Employee Benefit Plan
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995565 - Disclosure - Stockholders' Equity
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995575 - Disclosure - Share-based Compensation
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995585 - Disclosure - Financial Statement Schedules
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995595 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995605 - Disclosure - Fair Value Measurements (Tables)
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995615 - Disclosure - Loss per Share (Tables)
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995625 - Disclosure - Composition of Certain Financial Statement Captions (Tables)
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995635 - Disclosure - Commitments and Contingencies (Tables)
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995645 - Disclosure - Term Loan Obligations (Tables)
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995655 - Disclosure - Income Taxes (Tables)
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995665 - Disclosure - Share-based Compensation (Tables)
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995675 - Disclosure - Organization and Operations - Additional Information (Details)
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995685 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995695 - Disclosure - Fair Value Measurements - Additional Information (Details)
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995705 - Disclosure - Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details)
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995715 - Disclosure - Loss per Share - Schedule of Antidilutive Securities Excluded from Diluted Income (Loss) per Share (Details)
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995725 - Disclosure - Composition of Certain Financial Statement Captions - Other Current Assets (Details)
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995735 - Disclosure - Composition of Certain Financial Statement Captions - Property and Equipment, Net (Details)
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995745 - Disclosure - Composition of Certain Financial Statement Captions - Additional Information (Details)
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995755 - Disclosure - Composition of Certain Financial Statement Captions - Accounts Payable and Accrued Expenses (Details)
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995765 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995775 - Disclosure - Commitments and Contingencies - Summary of Lease Costs (Details)
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995785 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Annual Lease Payments under Operating Leases (Details)
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995795 - Disclosure - License Agreements - Additional Information (Details)
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995805 - Disclosure - Term Loan Obligations - Additional Information (Details)
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995815 - Disclosure - Term Loan Obligations - Term Loan Outstanding (Details)
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995825 - Disclosure - Term Loan Obligations - Future Payments under Obligation (Details)
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995835 - Disclosure - Commitments and Contingencies - Summary of Future Minimum Annual Lease Payments under Operating Leases (Details) 2
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995845 - Disclosure - Term Loan Obligations - Face Value to Book Value Reconciliation (Details)
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995855 - Disclosure - Grant Revenue - Additional Information (Details)
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995865 - Disclosure - Income Taxes - Additional Information (Details)
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995875 - Disclosure - Income Taxes - Reconciliation of Total Income Tax Provision (Details)
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995885 - Disclosure - Income Taxes - Deferred Tax Assets and Liabilities (Details)
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995895 - Disclosure - Income Taxes - Unrecognized Tax Benefits Activity (Details)
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995905 - Disclosure - Term Loan Obligations - Face Value to Book Value Reconciliation (Details) 2
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995915 - Disclosure - Employee Benefit Plan - Additional Information (Details)
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995925 - Disclosure - Stockholders' Equity - Preferred Stock (Details)
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995935 - Disclosure - Stockholders' Equity - Warrants (Details)
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995945 - Disclosure - Stockholders' Equity - Common stock (Details)
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995955 - Disclosure - Share-based Compensation - Additional Information (Details)
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995965 - Disclosure - Share-based Compensation - Stock Option Activity (Details)
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995975 - Disclosure - Share-based Compensation - Weighted-average Assumptions (Details)
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995985 - Disclosure - Share-based Compensation - Summary of Share-Based Compensation Recognized (Details)
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995995 - Disclosure - Subsequent Events - Additional Information (Details)
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Period for regain compliance
Period For Regain Compliance
Period for regain compliance.
Auditor Firm ID
Auditor Firm ID
2024
Lessee, Operating Lease, Liability, to be Paid, Year One
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Document Transition Report
Document Transition Report
Balance as of December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Income tax contingency.
Income Tax Contingency [Abstract]
Income Tax Contingency [Abstract]
Money Market [Member]
Money Market Funds [Member]
Payment of offering costs related to sale of common stock
Payment of offering costs related to sale of common stock
Payments of Stock Issuance Costs
Issuance costs paid in common stock
Geographical [Axis]
Geographical
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Stock option vesting period
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Entity Public Float
Entity Public Float
Schedule of Other Current Assets [Table Text Block]
Other Current Assets
Income Tax, Policy [Policy Text Block]
Income Taxes
Property, Plant and Equipment, Useful Life
Useful lives of the assets
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue recognized
Office, laboratory and storage space.
Office Laboratory And Storage Space [Member]
Office Laboratory and Storage Space [Member]
Prepaid Expense and Other Assets, Current [Abstract]
Other Current Assets [Abstract]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Total unamortized compensation cost related to outstanding unvested stock options and restricted stock awards
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase (decrease) in valuation allowance
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Summary of Share-Based Compensation Recognized
Two thousand twenty two distribution agreement.
Two Thousand Twenty Two Distribution Agreement [Member]
2022 Distribution Agreement [Member]
Schedule of right of use assets and lease liabilities.
Schedule Of Right Of Use Assets And Lease Liabilities Table [Text Block]
Summary of Lease Liabilities and Right-of-Use Assets
Issuance of common stock for in process research and development (in shares)
Stock Issued During Period, Shares, Issued for Services
Operating Lease, Liability, Noncurrent
Noncurrent operating lease liability
Operating lease liabilities. noncurrent
Stock Repurchased During Period, Shares
Number of stock repurchased
Lorem Vascular, Pte. Ltd.
Lorem Vascular Pte Ltd [Member]
Lorem Vascular Pte Ltd [Member]
Schedule of Stock by Class [Table]
Schedule Of Stock By Class [Table]
Treasury stock (at cost, 78,559 shares as of December 31, 2023)
Treasury stock (at cost, 78,559 shars as of December 31, 2023)
Treasury Stock, Common, Value
Piramal pharma solutions inc.
Piramal Pharma Solutions Inc [Member]
Piramal Pharma Solutions, Inc. [Member]
Debt Instrument, Unamortized Discount
Less: Debt discount
Debt Instrument, Unamortized Discount, Total
Class of Stock [Line Items]
Class of Stock [Line Items]
Cash Paid During Period For [Abstract]
Cash paid during period for:
Cash paid during period for:
Assets, Current
Total current assets
Purchase of treasury stock
Purchase of treasury stock
Payments for Repurchase of Equity
Payments for Repurchase of Equity, Total
Total liabilities and stockholders' equity (deficit)
Liabilities and Equity
Entity Address, State or Province
Entity Address, State or Province
Litigation Case [Domain]
Litigation Case
Deferred Tax Assets, Other
Other, net
Two thousand eighteen rights offering.
Two Thousand Eighteen Rights Offering [Member]
2018 Rights Offering [Member]
Issue and sale of stock, net
Stock Issued During Period, Value, New Issues
Issuance of common stock for exercise of warrants
Two thousand and twenty two purchase agreement.
Two Thousand and Twenty Two Purchase Agreement [Member]
2022 Purchase Agreement [Member]
Stock split conversion ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Balance as of December 31, 2023 (in shares)
Balance as of December 31, 2022 (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Resulting fair value
Goodwill and Intangible Assets, Policy [Policy Text Block]
Goodwill
Preferred stock dividend rate percentage eliminated date.
Preferred Stock Dividend Rate Percentage Eliminated Date
Series A 3.6% Convertible preferred stock eliminated date
Trading Symbol
Trading Symbol
Deferred Tax Assets, Net of Valuation Allowance
Total deferred tax assets, net of allowance
Common Stock, Shares, Issued
Common stock, shares issued (in shares)
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Share based compensation
Preferred stock, voting rights
Preferred Stock, Voting Rights
Interest Rate Floor [Member]
Interest Rate Floor [Member]
Rights related to distribution of assets
Rights Related To Distribution Of Assets
Rights related to distribution of assets.
Percentage of grant proceeds with interest not exceed annually.
Percentage Of Grant Proceeds With Interest Not Exceed Annually
Percentage of grant proceeds with interest not exceed annually
Compensation and Employee Benefit Plans [Text Block]
Employee Benefit Plan
Lease Expiration Date
Operating leases, expiration date
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Shares, Outstanding
Balance (in shares)
Balance (in shares)
2026
Lessee, Operating Lease, Liability, to be Paid, Year Three
Common stock capital shares reserved for future issuance
Increased in the total number of shares of common stock reserved for issuance
Number of shares reserved for issuance and sale
Components of Deferred Tax Liabilities [Abstract]
Deferred tax liabilities [Abstract]
Long-Term Debt, Current Maturities
Term loan obligation, current
Long-Term Debt, Current Maturities, Total
Term loan obligation, current
Entity Address, City or Town
Entity Address, City or Town
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, weighted average discount rate
Class of Warrant or Right, Outstanding
Class of warrant outstanding
Lessee, Operating Lease, Renewal Term
Lessee, operating lease, renewal term
Debt Disclosure [Text Block]
Term Loan Obligations
Property, Plant and Equipment [Table Text Block]
Property and Equipment, net
Subsequent Event [Member]
Subsequent Event [Member]
Subsequent Event Type [Axis]
Subsequent Event Type
UTHSA License Agreement.
U T H S A License Agreement [Member]
UTHSA License Agreement [Member]
Common stock, sales, available for issuance.
Common Stock Sales Available For Issuance
Remaining availability under financing facility
Deferred tax assets valuation allowances.
Deferred Tax Assets Valuation Allowances
Valuation allowance
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Property, Plant and Equipment, Net [Abstract]
Property and Equipment, net [Abstract]
Liabilities, Current [Abstract]
Current liabilities:
Assets, Current [Abstract]
Current assets:
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value (in dollars per share)
Impairment, Long-Lived Asset, Held-for-Use
Impairment loss
Impairment, Long-Lived Asset, Held-for-Use, Total
Statement of Stockholders' Equity [Abstract]
License agreement abstract.
License Agreement [Abstract]
Change in accounting principle, accounting standards update, immaterial effect
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Operating Lease, Liability, Current
Operating lease liability
Operating lease liabilities, current
Less: current portion
Second amendment to the amended and restated loan and security agreement.
Term Loan [Member]
Term Loan [Member]
Debt Instrument, Maturity Date
Maturity date
Derivative Contract [Domain]
Derivative Contract
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Equity Incentive Plans [Member]
Equity incentive plans.
Class of Stock [Domain]
Class of Stock
Series A convertible preferred stock.
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock [Member]
Investment Income, Interest
Interest income
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Income tax expense (benefit) at federal statutory rate
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Treasury stock, shares
Treasury Stock, Common, Shares
Entity Central Index Key
Entity Central Index Key
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Number of shares callable by warrants (in shares)
Number of securities called by warrant or right
Plan Name [Domain]
Plan Name
Change in accounting principle, accounting standards update, adopted
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Loss on disposal of property and equipment
Fair Value
Assets, Fair Value Disclosure
Assets, Fair Value Disclosure, Total
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Series F Preferred Stock [Member]
Liabilities, Current
Total current liabilities
Entity Tax Identification Number
Entity Tax Identification Number
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Increase (Decrease) in Operating Capital [Abstract]
Increases (decreases) in cash caused by changes in operating assets and liabilities:
September two thousand and twenty two distribution agreement.
September Two Thousand and Twenty Two Distribution Agreement [Member]
September 2022 Distribution Agreement [Member]
Financial Instruments [Domain]
Financial Instruments
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Share based compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Weighted Average Remaining Contractual Life (years) [Roll Forward]
Grant [Member]
Grant [Member]
Maximum value of shares to be issued under agreement.
Maximum Value of Shares to be Issued Under Agreement
Maximum value of shares to be issued under agreement
Services Agreement [Member]
Services Agreement [Member]
Services agreement.
Plan Name [Axis]
Plan Name
Derivative Instrument [Axis]
Derivative Instrument
Geographical [Domain]
Geographical
Lessee, Operating Lease, Term of Contract
Lessee, operating lease, term of contract
Assets
Total assets
Operating lease right-use-of assets
Operating lease right-of-use assets
Operating
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development studies.
Accrued Research And Development Studies
Accrued R&D studies
Common Class A [Member]
Common Class A [Member]
Entity Registrant Name
Entity Registrant Name
Components of Deferred Tax Assets [Abstract]
Deferred tax assets [Abstract]
Stock based compensation 2015 equity incentive plan 1 member.
Stock Based Compensation2015 Equity Incentive Plan1 [Member]
2015 Plan [Member]
Lessee, Operating Lease, Existence of Option to Extend [true false]
Lessee, operating lease, existence of option to extend [true false]
Related Party, Type [Domain]
Related Party
Recorded Unconditional Purchase Obligation [Line Items]
Recorded Unconditional Purchase Obligation [Line Items]
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Canaccord Genuity L L C Member
Canaccord Genuity L L C [Member]
Canaccord Genuity LLC [Member]
Canaccord Genuity LLC [Member]
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flows information:
Charlottesville
Charlottesville [Member]
Charlottesville [Member]
Retained Earnings [Member]
Accumulated Deficit [Member]
Long-Term Debt and Lease Obligation, Including Current Maturities
Total obligation
Liabilities, Fair Value Adjustment
Change in fair value of liability instruments
Class of Stock [Axis]
Class of Stock
Accrued vacation and compensation, current.
Accrued Vacation And Compensation Current
Accrued vacation and compensation
Minimum [Member]
Minimum [Member]
Effective income tax rate reconciliation tax return to provision.
Effective Income Tax Rate Reconciliation Tax Return To Provision
Return to provision
Revenue recognized
Revenues, Total
Revenue
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Lease liability
Operating Lease, Liability
Present value of obligations under leases
Leasehold Improvements, Gross
Leasehold improvements
Finance Lease, Liability
Finance lease obligation -- current
Finance Lease, Liability, Total
The expiration date of each operating loss carryforward included in total operating loss carryforwards, or the applicable range of such expiration dates.
Operating Loss Carryforwards Expiration Dates1
Net operating loss carryforwards, Expire date
Equity Component [Domain]
Equity Component
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Disclosure of accounting policy for license agreement.
License Agreement Disclosure [Text Block]
License Agreements
Amortization of Debt Issuance Costs and Discounts
Amortization of deferred financing costs and debt discount
Amortization of Debt Issuance Costs and Discounts, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Black-Scholes-Merton option valuation model based on weighted-average assumptions [Abstract]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Common stock issued for research and development
Common Stock Issued for Research and Development
Common stock issued for research and development.
Options.
Options [Member]
Outstanding Stock Options [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted Average Exercise Price [Roll Forward]
Debt Disclosure [Abstract]
Debt Instrument, Basis Spread on Variable Rate
Basis variable rate
Entity Current Reporting Status
Entity Current Reporting Status
Common Stock, Shares Authorized
Common stock, shares authorized (in shares)
Research and development
Research and development expense
Research and Development Expense
Research and Development Expense, Total
Fair Value, by Balance Sheet Grouping [Table]
Fair Value By Balance Sheet Grouping [Table]
Debt, Policy [Policy Text Block]
Deferred Financing Costs and Other Debt-Related Costs
Deferred Tax Liabilities, Gross
Total deferred tax liability
Deferred Tax Liabilities, Gross, Total
Stock Repurchase Program Authorized Dollar Amount
Authorized amount of repurchase of stock
Share-Based Payment Arrangement, Activity [Table Text Block]
Stock Option Activity
Other.
Other
Other
Assets [Abstract]
Assets
Gross proceeds from sale of common stock
Proceeds from Issuance of Common Stock
Proceeds from sale of common stock, net
Grant Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Amortization of Intangible Assets
Amortization
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Securities remaining and available for future issuances (in shares)
Convertible Preferred Stock [Member]
Common stock, $0.001 par value; 100,000,000 shares authorized; 4,522,656 issued and 4,444,097 outstanding as of December 31, 2023, 2,240,092 shares issued and outstanding as of December 31, 2022, respectively
Common Stock, Value, Issued
Voting stock, value
Debt Instrument, Offering Date
Origination date
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Repayments of Long-Term Debt
Principal payments of long-term obligations
Repayments of Long-Term Debt, Total
Payment for tech transfer and validation fee
Payment For Tech Transfer And Validation Fee
Payment for tech transfer and validation fee.
Current Fiscal Year End Date
Current Fiscal Year End Date
Lincoln park capital fund, LLC.
Lincoln Park Capital Fund L L C [Member]
Lincoln Park Capital Fund, LLC [Member]
Share-Based Payment Arrangement, Noncash Expense
Share-based compensation expense
Share-Based Payment Arrangement, Noncash Expense, Total
Auditor Name
Auditor Name
Operating Income (Loss)
Operating loss
Accounting Standards Update 2019-12 [Member]
ASU 2019-12 [Member]
Consideration paid to preferred stock holders
Consideration Paid To Preferred Stock Holders
Consideration paid to preferred stock holders.
Income Tax Expense (Benefit)
Provision or benefit for income taxes
Income Tax Expense (Benefit), Total
Effective Income Tax Rate Reconciliation, Tax Settlement, State and Local, Percent
Change in state rate
Research and Development Expense [Member]
Research and Development [Member]
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Gross decreases – tax positions in prior period
Contractual Obligation, Fiscal Year Maturity [Table Text Block]
Future Payments under Obligation
Loan and security agreement.
Loan And Security Agreement [Member]
Loan and Security Agreement [Member]
SEC Schedule, 12-09, Valuation and Qualifying Accounts [Abstract]
Refers to the period exercisable from the date of issuance.
Period Exercisable From The Date Of Issuance
Period exercisable from the date of issuance
Indefinite-Lived Intangible Assets [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Stock option vesting percentage
Consecutive business days
Consecutive Business Days
Consecutive business days.
Increase (Decrease) in Operating Lease Liability
Change in operating lease liabilities
Contract effective date.
Contract Effective Date
Contract effective date
Revenue from Contract with Customer [Text Block]
Grant Revenue
Balance as of December 31, 2023
Balance as of December 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Debt Instrument, Face Amount
Original loan amount
Earnings Per Share, Policy [Policy Text Block]
Loss Per Share
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Gross increase – current-period tax positions
Sale of Stock, Price Per Share
Sale of Stock, Price Per Share
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Operating Leases
Operating Expenses [Abstract]
Operating expenses:
Entity Voluntary Filers
Entity Voluntary Filers
Subsequent Events [Abstract]
Sales order cost.
Sales Order Cost
Sales order cost
Income taxes.
Income Taxes [Table]
Income Taxes [Table]
Commitments and Contingencies Disclosure [Abstract]
Other Assets, Noncurrent
Other assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted (in shares)
Common stock shares to be issued (in shares)
Equity [Text Block]
Stockholders' Equity
Depreciation
Depreciation expense
Depreciation, Total
Interest Paid, Excluding Capitalized Interest, Operating Activities
Interest
Initial commitment shares.
Initial Commitment Shares
Initial commitment shares
Sale of the japanese subsidiary and certain assets.
Sale Of Japanese Subsidiary And Certain Assets [Member]
Sale of the Japanese Subsidiary and Certain Assets [Member]
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Total
Common Class B [Member]
Common Class B [Member]
Vested and expected to vest at December 31, 2023 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Stockholders' equity (deficit):
Equity, Attributable to Parent [Abstract]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Lease, Cost [Table Text Block]
Summary of Lease Costs
Entity [Domain]
Entity
Number of Reporting Units
Number of reporting units
Amount of lessee's undiscounted obligation for lease payments for operating lease, due after fourth fiscal year following latest fiscal year.
Lessee Operating Lease Liability Payments Due After Year Four
Thereafter
Commitment fee.
Commitment Fee [Member]
Commitment Fee [Member]
Earnings Per Share [Abstract]
Summary of Future Minimum Annual Lease Payments under Operating Leases
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
Litigation Case [Axis]
Litigation Case
Deferred Tax Liabilities, Net
Net deferred tax assets (liability)
Accounting Policies [Abstract]
In Process Research and Development [Member]
Contract termination date.
Contract Termination Date
Contract termination date
Schedule of operating and financing lease liability maturity.
Schedule Of Operating And Financing Lease Liability Maturity Table [Text Block]
Summary of Future Minimum Annual Lease Payments under Operating and Financing Leases
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration Risk
Consideration to purchaser in cash
Sale of Stock, Consideration Received on Transaction
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Cash Equivalents, at Carrying Value
Cash equivalents investments with original maturities
Cash Equivalents, at Carrying Value, Total
Commitments and Contingencies
Commitments and contingencies (Note 6)
Income Statement [Abstract]
Related Party, Type [Axis]
Related Party
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Cash paid for amounts included in the measurement of lease liabilities.
Cash Paid For Amounts Included In Measurement Of Lease Liabilities
Total cash paid for amounts included in the measurement of lease liabilities
Percentage of net operating loss carryforwards available for offsetting against future taxable income.
Percentage Of Net Operating Loss Carryforwards Available For Offsetting Against Future Taxable Income
Percentage of federal net operating losses used to offset of future taxable income
Operating Lease, Cost
Operating lease expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Interest related to unrecognized tax benefits in interest expense and penalties
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Retirement Benefits [Abstract]
Grant funding term.
Grant Funding Term
Grant funding term
Increase in grant revenue
Increase (Decrease) in Grant Revenue
Increase (decrease) in grant revenue.
Vested and expected to vest at December 31, 2023 (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Statistical Measurement [Domain]
Statistical Measurement
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Net cash used in operating activities
Document Period End Date
Document Period End Date
Annual increase in lease rate
Annual Increase In Lease Rate
Annual increase in lease rate
Statistical Measurement [Axis]
Statistical Measurement
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Stockholders' Equity Note [Abstract]
Operating Lease, Payments
Operating cash used for operating leases
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share, diluted
Product and Service [Domain]
Product and Service
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Federal tax carry forward
Lease, Cost [Abstract]
Lease expense:
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Deferred tax assets related to NOL carryforwards
Identified eligible reimbursable costs
Reimbursement Costs Incurred
Reimbursement costs incurred.
Unrecognized Tax Benefits
Unrecognized Tax Benefits – Ending
Unrecognized Tax Benefits – Beginning
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
State tax credit carryforwards
Internal Revenue Service (IRS) [Member]
Internal Revenue Code [Member]
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Research credit
Revenue from Contract with Customer [Abstract]
Redemption of Series F preferred stock (in shares)
Stock Redeemed or Called During Period, Shares
Debt Instrument, Name [Domain]
Debt Instrument, Name
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Exercisable at December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Expected volatility
Recurring Basis [Member]
Fair Value, Recurring [Member]
Lease commencement date.
Lease Commencement Date
Lease commencement date
LIBOR [Member]
LIBOR.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Options [Roll Forward]
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Components of Deferred Tax Assets and Liabilities [Abstract]
Portions of the deferred tax assets and deferred tax liabilities [Abstract]
Representative Series U Warrant.
Representative Series U Warrant [Member]
Representative Warrants [Member]
Initial commitment fee.
Initial Commitment Fee
Initial commitment fee paid in cash
Aggregate expense including fee and disbursement expenses.
Aggregate Expense Including Fee and Disbursement Expenses
Reimburse of fee and disbursements expenses
Series F Convertible Preferred Stock [Member]
Series F Convertible Preferred Stock.
Liabilities and Stockholders' Equity (Deficit)
Liabilities and Equity [Abstract]
The date that the warrant or right expires.
Class Of Warrant Or Right Expiration Date
Warrant expiration date
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Interactive Data Current
Entity Interactive Data Current
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Percentage of matching contribution for employee contributions
Common stock issued in payment for in process research and development
Stock Issued
Preferred Stock, Dividend Rate, Percentage
Convertible preferred stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Expected Dividend
Dividend yield assumed
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: amount representing interest
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Compensatory damages and operational.
Compensatory Damages And Operational
Compensatory damages and operational
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and cash equivalents
Aggregated Intrinsic Value [Roll Forward]
Share Based Compensation Arrangement by Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Share based compensation arrangement by share based payment award options aggregate intrinsic value.
Liability for Uncertainty in Income Taxes, Current
Liability for uncertain tax positions
Equity Components [Axis]
Equity Components
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Refers to cumulative change in ownership in percentage.
Cumulative Change In Ownership
Cumulative change in ownership
Deferred Tax Assets, Property, Plant and Equipment
Property and equipment, principally due to differences in depreciation
Nano Tx license agreement Member
Nano Tx Licenses Agreement [Member]
Nano Tx Licenses Agreement [Member]
Percentage issuance of common stock.
Percentage Issuance Of Common Stock
Percentage issuance of common stock
Local Phone Number
Local Phone Number
Sale of Stock [Axis]
Sale of Stock
Exercisable at December 31, 2023 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Operating leases, expiry year.
Operating Leases Expiry Year
Operating leases expiry year
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Goodwill
Goodwill
Goodwill, Total
Goodwill, Beginning Balance
Goodwill, Ending Balance
Refers to the period of net operating loss and R&D tax credit carry forwards to offset future taxable income.
Net Operating Loss And Research And Development Tax Credit Carry Forwards To Offset Future Taxable Income Period
Period of net operating loss and R&D tax credit carry forwards to offset future taxable income
Statement of Cash Flows [Abstract]
Percentage of non-dilutive monetary awards required to pay.
Percentage of Non-dilutive Monetary awards Required to Pay
Percentage of non-dilutive monetary awards required to pay
Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]
Fair Value Measurements
Series C convertible preferred stock.
Series C Convertible Preferred Stock [Member]
Series C Convertible Preferred Stock [Member]
Income Tax Authority [Domain]
Income Tax Authority
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Document Annual Report
Document Annual Report
Common Stock, Par or Stated Value Per Share
Common stock, par value (in dollars per share)
Contractual obligation to provide funding of research and development costs over periods that initially exceed one year or the normal operating cycle, if longer.
Pre Clinical Research Study Obligations [Member]
Pre-clinical Research Study Obligations [Member]
Debt Instrument, Interest Rate, Stated Percentage
Interest Rate
Refers to period for material changes of liability for uncertain tax benefits.
Period For Material Changes Of Liability For Uncertain Tax Benefits
Period for material changes of liability for uncertain tax benefits
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Weighted average period for recognition of cost
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Vested and expected to vest at December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Reconciliation of the total income tax provision tax rate [Abstract]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Maximum [Member]
Maximum [Member]
Option for exclusive worldwide license
Option For Exclusive Worldwide License
Option for exclusive worldwide license.
Income Tax Examination, Penalties and Interest Expense
Interest or penalties related to income tax matters
Income Tax Examination, Penalties and Interest Expense, Total
Contractual Obligation, to be Paid, Year One
2023
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Organization and Operations
Outstanding Warrants and Options [Member]
Outstanding warrants and options.
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Unrecognized Tax Benefits Activity
Series B convertible preferred stock.
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Share-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Fair Value, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Adjustment of Warrants
Change in fair value of liability instruments
Net decrease in cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
General and Administrative Expense [Member]
General and Administrative [Member]
January two thousand and twenty two distribution agreement.
January Two Thousand and Twenty Two Distribution Agreement [Member]
January 2022 Distribution Agreement [Member]
Percentage of aggregate amount of proceeds awarded under CPRIT grant.
Percentage Of Aggregate Amount Of Proceeds Awarded Under CPRIT Grant
Percentage of aggregate amount of proceeds awarded under CPRIT grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Cancelled/forfeited (in shares)
Number Of Votes Per Share
Number Of Votes Per Share
Number of votes per share.
Document Financial Statement Error Correction [Flag]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Diluted Income (Loss) per Share
Closing bid price for common stock had fallen below
Closing Bid Price For Common Stock Had Fallen Below
Closing bid price for common stock had fallen.
Payments for Royalties
License fee payment in cash
City Area Code
City Area Code
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows used in operating activities:
Accounts Payable and Accrued Liabilities [Abstract]
Accounts Payable and Accrued Expenses [Abstract]
Sale closed date
Sale of Stock, Transaction Date
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Standard Product Warranty, Policy [Policy Text Block]
Warrant Liability
Basic weighted average shares used in calculating net loss per share attributable to common stockholders
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Tax credit carryforward, expiration date
Expiration date of the tax credit carryforward.
Tax Credit Carryforward Expiration Date1
CPRIT grant funding term.
CPRIT Grant Funding Term
CPRIT grant funding term, description
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Research and Development Expense, Policy [Policy Text Block]
Research and Development
SEC Schedule, 12-09, Schedule of Valuation and Qualifying Accounts Disclosure [Text Block]
Financial Statement Schedules
Statement [Table]
Statement [Table]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Weighted-average Assumptions
Document Fiscal Period Focus
Document Fiscal Period Focus
Lessee, Operating Lease, Liability, to be Paid
Minimum lease payment
Total minimum lease payments
Long term debt outstanding threshold amount.
Long Term Debt Outstanding Threshold Amount
Long Term Debt Outstanding Threshold Amount
Long term debt outstanding threshold amount
2025
Lessee, Operating Lease, Liability, to be Paid, Year Two
Accrued Professional Fees, Current
Accrued professional fees
Statement [Line Items]
Statement [Line Items]
Master services agreement Terms description.
Master Services Agreement Terms Description
Master services agreement terms, Description
Schedule of Long-Term Debt Instruments [Table Text Block]
Term Loan Outstanding
Net operating loss carryforward.
Net Operating Loss Carryforward
Net operating losses
Payments to acquire property plant and equipment and intangible assets.
Payments To Acquire Property Plant And Equipment And Intangible Assets
Purchases of property and equipment and intangible assets
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Dilutive common shares excluded from the calculations of diluted loss per share (in shares)
Lease, Cost
Total lease expense
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Twenty twenty purchase agreement.
Twenty Twenty Purchase Agreement [Member]
2020 Purchase Agreement [Member]
Warrant [Member]
Outstanding Warrants [Member]
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Deferred Tax Assets and Liabilities
Number of warrants exercised
Number Of Warrants Exercised
Number of warrants exercised
Deferred grant liability
Increase Decrease In Deferred Grant Liability
Increase (decrease) in deferred grant liability.
Composition of Certain Financial Statement Captions [Abstract]
Composition Of Certain Financial Statement Captions [Abstract]
Common Stock [Member]
Common Stock [Member]
Organization and Operations [Line Items]
Organization and operations.
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Distribution agreement member.
Distribution Agreement [Member]
2020 Distribution Agreement [Member]
2020 Repurchase Agreement.
Twenty Twenty Repurchase Agreement [Member]
2020 Repurchase Agreement [Member]
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Other Assets, Current
Other current assets
Total other current assets
Exercisable at December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Fair Value of Financial Instruments, Policy [Policy Text Block]
Financial Instruments
ASU 2016-13
Accounting Standards Update 2016-13 [Member]
Schedule of Debt [Table Text Block]
Face Value to Book Value Reconciliation
Treasury stock
Treasury Stock, Value
Treasury Stock, Value, Total
Cover
Cover [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
This represents contract with BARDA to develop a new countermeasure for thermal burns entitling the company to be reimbursed for qualifying expenditures.
Qualifying Expenditures Related To Research And Development Expense
Qualifying expenditures related to research
Number of maximum common shares can be resale.
Number of Maximum Common Shares Can Be Resale
Number of maximum common shares can be resale
Litigation Settlement, Expense
Litigation settlement, expense
Sale of Stock [Domain]
Sale of Stock
Preferred Stock [Member]
Convertible Preferred Stock [Member]
Medidata Solutions, Inc. [Member]
Medidata Solutions Inc [Member]
Medidata solutions, inc.
Share-Based Payment Arrangement [Policy Text Block]
Share-Based Compensation
Security Exchange Name
Security Exchange Name
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Stock option contractual term
Domestic Tax Authority [Member]
Federal [Member]
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Issued Accounting Pronouncements
Preferred Stock, Shares Issued
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Authorized
Preferred stock, shares authorized (in shares)
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to net operating loss expiration.
Effective Income Tax Rate Reconciliation Net Operating Loss Expiration
NOLs expiring and adjustments to NOL
Property, Plant and Equipment, Gross
Property and equipment, gross
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Cash payment information.
Cash Payment Information [Abstract]
Cash payment information:
Right-of-use assets acquired by assuming operating lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Purchase of treasury stock (in Shares)
Purchase of treasury stock (in Shares)
Treasury Stock, Shares, Acquired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled/forfeited (in dollars per share)
At the market offering program.
At The Market Offering Program [Member]
At The Market Offering Program [Member]
Legal Entity [Axis]
Legal Entity
Financial Instrument [Axis]
Financial Instrument
Warrants and Rights Outstanding, Term
Warrants expected term
Stock Issued During Period, Value, Stock Options Exercised
Stock options exercised
Entity Emerging Growth Company
Entity Emerging Growth Company
Exercisable at December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Amendment Flag
Amendment Flag
Reverse stock split effective date
Reverse Stock Split Effective Date
Reverse stock split effective date.
Accounting Standards Update [Domain]
Accounting Standards Update
Shares issued
Shares, Issued
Remaining common stock issued and sold (in shares)
Variable Rate [Domain]
Variable Rate
Entity File Number
Entity File Number
Debt instrument amended expiration date.
Debt Instrument Amended Expiration Date
Amended expiration date
Contractual Obligation, to be Paid, Year Two
2024
Deferred Tax Assets, Gross
Deferred tax assets (Total)
Class of Warrant or Right, Date from which Warrants or Rights Exercisable
Date from which warrants are exercisable
Long-Term Debt, Excluding Current Maturities
Term loan obligation
Long-Term Debt, Excluding Current Maturities, Total
Single-Stock Future [Member]
Single Regular Purchase [Member]
Biocept Agreement [Member]
Biocept Agreement [Member]
Biocept Agreement.
Reconciliation of Face Value to Book Value [Abstract]
Debt Instrument Reconciliation Of Face Value To Book Value [Abstract]
Reconciliation of Face Value to Book Value [Abstract]
Recorded Unconditional Purchase Obligation [Table]
Recorded Unconditional Purchase Obligation [Table]
Share-Based Payment Arrangement [Abstract]
Stock-based Compensation [Abstract]
Deferred Income, Noncurrent
Deferred grant liability
Disposal Group Classification [Domain]
Disposal Group Classification
Accrued license payable.
Accrued License Payable
Accrued payments due to NanoTx
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Debt Instrument [Axis]
Debt Instrument
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Debt Instrument, Periodic Payment
Current Monthly Payment
Debt Instrument, Periodic Payment, Total
Operating Expenses
Total operating expenses
Other Intangible Assets, Net
Intangible assets, net
Auditor Location
Auditor Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term
Entity Address, Address Line Two
Entity Address, Address Line Two
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Preferred stock, $0.001 par value; 5,000,000 shares authorized; 1,952 shares issued and outstanding as of December 31, 2023 and 2022
Preferred Stock, Value, Issued
Entity Small Business
Entity Small Business
Entity Shell Company
Entity Shell Company
Number of Operating Segments
Number of operating segment
Investment Type [Axis]
Investment Type
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrant exercise price (in dollars per share)
Accrued Bonuses, Current
Accrued payroll and bonus
Gross proceeds from issuance of common stock.
Gross Proceeds from Issuance of Common Stock
Aggregate gross proceeds from sales of common stock
Class of Warrant or Right [Domain]
Class of Warrant or Right
Earnings Per Share [Text Block]
Loss per Share
Series U warrants member
Series U Warrants [Member]
Series U Warrants [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Contractual Obligation
Contractual obligation
Total
Total debt obligations, including final payment fee (Face Value)
Other Liabilities, Current
Other current liabilities
Supplemental Balance Sheet Disclosures [Text Block]
Composition of Certain Financial Statement Captions
Subsequent Event Type [Domain]
Subsequent Event Type
Income Statement Location [Axis]
Income Statement Location
Rule 10b51 Arrangement Modified
Rule 10b51 Arr Modified [Flag]
Rule 10b51 Arr Modified Flag.
Maximum grant amount to be received as per grant contract.
Maximum Grant Amount to be Received as per Grant Contract
Maximum grant amount to be received as per grant contract
Organization and Operations [Table]
Organization and Operations [Table]
Amortization of Debt Discount (Premium)
Non-cash amortization
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Accrued expenses
Sales order term
Sales Order Term
Sales order term.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividends
Prepaid Insurance
Prepaid insurance
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Fractional adjustment
Fractional Adjustment of Common Stock
Fractional adjustment of common stock.
Long-Term Debt, Gross
Remaining Principal (Face Value)
Master services agreement date.
Master Services Agreement Date
Master service agreement date
Depreciation, Depletion and Amortization
Depreciation and amortization
Depreciation, Depletion and Amortization, Total
Product and Service [Axis]
Product and Service
Purchase of treasury stock
Purchase of treasury stock
Treasury Stock, Value, Acquired, Cost Method
Master services agreement initial term.
Master Services Agreement Initial Term
Master services agreement initial term
Common stock, reverse stock split, fractional shares issued
Stock Issued During Period, Shares, Stock Splits
Percentage of commission on gross proceeds from sale of common stock.
Percentage of Commission on Gross Proceeds from Sale of Common Stock
Percentage of commission on gross proceeds from sale of common stock
Title of 12(b) Security
Title of 12(b) Security
TEXAS
San Antonio, Texas [Member]
In process research and development acquired
Cash Paid For I P R D Asset Acquired In An Asset Acquisition
Cash paid for IPRD asset acquired in an asset acquisition.
Income Tax Authority, Name [Axis]
Summary of Financial Assets Measured at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Investments [Domain]
Investments
Accounting Standards Update [Axis]
Accounting Standards Update
Treasury Stock [Member]
Treasury Stock, Common [Member]
Subscription Agreement [Member]
Subscription Agreement [Member]
Additional details relating term loan that is outstanding [Abstract]
Additional Details Relating Term Loan That Is Outstanding [Abstract]
Additional details relating term loan that is outstanding [Abstract]
Cash flows used in investing activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Development.
Development [Member]
Development [Member]
Unpaid Offering Costs.
Unpaid Offering Costs
Unpaid offering cost
Accounts Payable and Accrued Liabilities, Current
Accounts payable and accrued expenses
Accounts payable and accrued expenses, Total
State and Local Jurisdiction [Member]
State [Member]
Segment Reporting, Policy [Policy Text Block]
Segment Information
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Subsequent Event [Table]
Subsequent Event [Table]
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents [Axis]
Income taxes.
Income Taxes [Line Items]
Income Taxes [Line Items]
Defined Contribution Plan, Employer Discretionary Contribution Amount
Discretionary or matching contributions
Exercisable at December 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Common Stock, Shares, Outstanding
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Share-Based Payment Arrangement [Text Block]
Share-based Compensation
Sales agreement.
Sales Agreement [Member]
Sales Agreement [Member]
Contractual Obligation, Fiscal Year Maturity [Abstract]
Future contractual principal and final fee payments on all debt [Abstract]
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Schedule of reconciliation of unrecognized tax benefits activity [Roll Forward]
Operating lease discount rate
Lessee, Operating Lease, Discount Rate
Income Statement Location [Domain]
Income Statement Location
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted (in dollars per share)
Represents a contract to develop a new countermeasure for thermal burns with the U.S. Department of Health and Human Service's Biomedical Advanced Research and Development Authority (BARDA).
Barda Contract [Member]
BARDA Contract [Member]
Document Type
Document Type
Other Prepaid Expense, Current
Prepaid services
Debt Instrument, Fee Amount
Fees amount associated with loan
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Disposal Group Classification [Axis]
Disposal Group Classification
Deferred Tax Liabilities, Other
Other
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Entity Filer Category
Entity Filer Category
Number Of Preferred Stock Shares Exercised.
Number Of Preferred Stock Shares Exercised
Number of preferred stock, shares converted
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental schedule of non-cash investing and financing activities:
Recorded Unconditional Purchase Obligation by Category of Item Purchased [Axis]
Recorded Unconditional Purchase Obligation by Category of Item Purchased
Other assets
Other assets
Increase (Decrease) in Other Noncurrent Assets
Income Tax Authority, Name [Domain]
Variable Rate [Axis]
Variable Rate
Total other income (expense)
Nonoperating Income (Expense)
Deferred Tax Assets, Tax Credit Carryforwards
Income tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Total
Liabilities
Total liabilities
Non Rule 10b51 Arrangement Modified
Non Rule 10b51 Arr Modified [Flag]
Non rule 10b51 arr modified flag.
Property, Plant and Equipment, Impairment [Policy Text Block]
Impairment
Asset Impairment Charges
Impairment charges
Asset Impairment Charges, Total
Total stockholders' equity (deficit)
Stockholders' deficit
Equity, Attributable to Parent
Balance
Balance
The gross amount of office and computer equipment cost as of the balance sheet date.
Office And Computer Equipment Gross
Office and computer equipment
Stock issued during period reverse stock splits, shares
Stock Issued During Period, Shares, Reverse Stock Splits
Net loss
Net loss
Interest Expense
Interest expense
Interest expense
Interest Expense, Total
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents [Domain]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Income tax expense (benefit) at state statutory rate
Statement of Financial Position [Abstract]
Diluted weighted average shares used in calculating net loss per share attributable to common stockholders
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Reconciliation of Total Income Tax Provision
Reduction in the carrying amount of operating lease right-of-use assets
Operating Lease, Right-of-Use Asset, Periodic Reduction
Effective Income Tax Rate Reconciliation, Percent
Total income tax provision
Other Income and Expenses [Abstract]
Other income (expense):
In Process Research and Development, Policy [Policy Text Block]
Acquired In-Process Research and Development (IPR&D)
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Accounts Payable and Accrued Expenses
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, weighted average remaining term
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Income Tax Disclosure [Text Block]
Income Taxes
Issuance of common stock for in process research and development
Stock Issued During Period, Value, Issued for Services
Balance as of December 31, 2023 (in dollars per share)
Balance as of December 31, 2022 (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Unconditional Purchase Obligation, Category of Goods or Services Acquired [Domain]
Unconditional Purchase Obligation, Category of Goods or Services Acquired
Floating interest rate for funds borrowed, under the debt agreement.
Debt Instrument Floating Interest Rate Percentage
Interest rate
Cancer prevention and research institute of texas contract.
Cancer Prevention And Research Institute Of Texas Contract [Member]
CPRIT Contract [Member]
Disaggregation of Revenue [Line Items]
Income Tax Authority [Axis]
Income Tax Authority
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Fair Value Disclosures [Abstract]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Measurement Frequency [Domain]
Measurement Frequency [Domain]
Stock based compensation 2020 equity incentive plan.
Stock Based Compensation2020 Equity Incentive Plan [Member]
2020 Plan [Member]
Issue and sale of share
Issue and sale of share
Sale of common stock, net (in shares)
Warrants issued, underwritten public offering, period
Warrants Issued Underwritten Public Offering Period
Warrants issued, underwritten public offering, period.
Operating Lease, Expense
Rent expense
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash and cash equivalents at end of period
Cash and cash equivalents at beginning of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Debt Instrument, Covenant Compliance
Debt instrument, covenant compliance
Class of Warrant or Right [Axis]
Class of Warrant or Right
Income Tax Disclosure [Abstract]
Operating Loss Carryforwards
Tax loss carryforwards