CORRESP

PLUS THERAPEUTICS, INC.

4200 Marathon Blvd.

Suite 200

Austin, TX 78756

September 8, 2021

VIA EDGAR

Division of Corporation Finance

U.S. Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

 

  Re:

Plus Therapeutics, Inc.

      

Registration Statement on Form S-1 (File No. 333-259325)

      

Request for Acceleration of Effective Date

Ladies and Gentlemen:

Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended, Plus Therapeutics, Inc., a Delaware corporation, hereby requests that the Securities and Exchange Commission accelerate the effective date of the above-referenced Registration Statement on Form S-1 (File No. 333-259325) and declare the Registration Statement effective as of Friday, September 10, 2021, at 5:00 p.m., Eastern time, or as soon as practicable thereafter.

Please contact the undersigned at (737) 255-7194, or Nicholas Griffin of Hogan Lovells US LLP at (713) 632-1488 with any questions. Also, please notify Mr. Griffin when this request for acceleration has been granted.

 

Very truly yours,
PLUS THERAPEUTICS, INC.
By:  

/s/ Andrew Sims

  Name: Andrew Sims
  Title: Chief Financial Officer

 

cc:

Nicholas Griffin, Hogan Lovells US LLP